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经尿道前列腺单极与双极切除术治疗良性前列腺增生:手术结果与术者偏好,真实世界情况

Monopolar versus bipolar transurethral resection of prostate for benign prostatic hyperplasia: Operative outcomes and surgeon preferences, a real-world scenario.

作者信息

Madduri Vijay Kumar Sarma, Bera Malay Kumar, Pal Dilip Kumar

机构信息

Department of Urology, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.

出版信息

Urol Ann. 2016 Jul-Sep;8(3):291-6. doi: 10.4103/0974-7796.184900.

Abstract

CONTEXT

Monopolar transurethral resection of prostate (M-TURP) is considered the gold standard for the management of bladder outlet obstruction due to benign prostatic hyperplasia. Its newly introduced modification, bipolar TURP (B-TURP), promises to overcome its most prominent shortcomings, namely bleeding and dilutional hyponatremia. Literature is conflicting regarding merits of B-TURP over M-TURP.

AIMS

To find a difference, if any, in perioperative outcomes between M-TURP and B-TURP in a real-wold setting.

SETTINGS AND DESIGN

Prospective nonrandomized study.

SUBJECTS AND METHODS

Operative outcomes of patients undergoing M-TURP and B-TURP from February 2014 to October 2015 were compared.

STATISTICAL ANALYSIS USED

Categorical data were compared by Fischer exact test and numerical data were compared by independent samples Mann-Whitney U-test. P <0.05 was considered statistically significant.

RESULTS

The mean size of prostate operated by bipolar technology was significantly greater than those operated by monopolar technology (38.12 ± 9.59 cc vs. 66.49 ± 22.95 cc; P < 0.001). The mean fall in postoperative serum sodium concentration was 0.99 ± 0.76 mEq/L for the B-TURP group as compared to 3.60 ± 2.89 mEq/L for the M-TURP group (P < 0.001). The mean drop in postoperative hemoglobin concentration (P = 0.28) was statistically insignificant, even though larger glands were operated by B-TURP. There were three instances of the transurethral resection (TUR) syndrome in the M-TURP group whereas no TUR syndrome occurred in the B-TURP group.

CONCLUSIONS

In spite of various contrary viewpoints in literature, surgeons prefer to operate on larger prostates using bipolar technology. B-TURP definitely reduces the incidence of bleeding and dilutional hyponatremia, making it a contender to replace M-TURP as the new gold standard.

摘要

背景

经尿道前列腺单极切除术(M-TURP)被认为是治疗良性前列腺增生所致膀胱出口梗阻的金标准。其新引入的改良术式,双极经尿道前列腺切除术(B-TURP)有望克服其最突出的缺点,即出血和稀释性低钠血症。关于B-TURP相对于M-TURP的优点,文献观点不一。

目的

在实际临床环境中,找出M-TURP和B-TURP围手术期结局的差异(若存在差异)。

设置与设计

前瞻性非随机研究。

研究对象与方法

比较2014年2月至2015年10月期间接受M-TURP和B-TURP治疗的患者的手术结局。

所用统计分析方法

分类数据采用Fisher确切检验进行比较,数值数据采用独立样本曼-惠特尼U检验进行比较。P<0.05被认为具有统计学意义。

结果

采用双极技术切除的前列腺平均大小显著大于采用单极技术切除的前列腺(38.12±9.59立方厘米对66.49±22.95立方厘米;P<0.001)。B-TURP组术后血清钠浓度平均下降0.99±0.76毫当量/升,而M-TURP组为3.60±2.89毫当量/升(P<0.001)。尽管B-TURP用于切除更大的腺体,但术后血红蛋白浓度的平均下降(P=0.28)无统计学意义。M-TURP组有3例经尿道电切(TUR)综合征,而B-TURP组未发生TUR综合征。

结论

尽管文献中有各种相反观点,但外科医生更倾向于使用双极技术对更大的前列腺进行手术。B-TURP确实降低了出血和稀释性低钠血症的发生率,使其成为取代M-TURP成为新金标准的有力竞争者。

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