Nguyen-Khac Florence, Daudignon Agnès, Eclache Virginie, Lafage-Pochitaloff Marina, Lefebvre Christine, Luquet Isabelle, Penther Dominique
UPMC Paris 6, Inserm UMRS 1138, Hôpital de la Pitié-Salpêtrière, Paris, France.
UF de cytogénétique hématologique, Pôle biologie-hygiène, Centre hospitalier de Valenciennes, France.
Ann Biol Clin (Paris). 2016 Oct 1;74(5):509-510. doi: 10.1684/abc.2016.1150.
Cytogenetic analysis is still important in the management of many hematological malignancies, despite the new techniques available such as the high-throughput sequencing analysis, and the discovery of many acquired gene mutations in these diseases. The Groupe francophone de cytogénétique hématologique (GFCH) published in 2004 the recommendations for the cytogenetic management of hematological malignancies. It reports here the update of these recommendations, with a review of the literature for each disease.
尽管有高通量测序分析等新技术,且在这些疾病中发现了许多获得性基因突变,但细胞遗传学分析在许多血液系统恶性肿瘤的管理中仍然很重要。法语国家血液学细胞遗传学小组(GFCH)于2004年发表了血液系统恶性肿瘤细胞遗传学管理的建议。本文报告了这些建议的更新内容,并对每种疾病的文献进行了综述。