接受永久性希氏束起搏的束支传导阻滞患者QRS波变窄的生理机制
Physiological mechanisms of QRS narrowing in bundle branch block patients undergoing permanent His bundle pacing.
作者信息
Teng Alexandra E, Massoud Louis, Ajijola Olujimi A
机构信息
UCLA Cardiac Arrhythmia Center, Los Angeles, CA.
UCLA Cardiac Arrhythmia Center, Los Angeles, CA.
出版信息
J Electrocardiol. 2016 Sep-Oct;49(5):644-8. doi: 10.1016/j.jelectrocard.2016.07.013. Epub 2016 Jul 16.
Abstract
His bundle pacing is increasingly used to avoid chronic right ventricular pacing, and electrically resynchronize ventricular activation by narrowing or normalizing the QRS interval in left and right bundle branch block. The mechanisms by which this occurs remain poorly understood. In this review, the proposed mechanisms and evidence supporting them are discussed. Also discussed are aspects of mechanisms that are not completely supported by the evidence. We also review the differences and physiological bases for direct vs. indirect His bundle capture, and the physiological mechanisms for QRS narrowing vs. normalization following His bundle pacing.
摘要
希氏束起搏越来越多地用于避免长期右心室起搏，并通过缩窄或使左、右束支传导阻滞时的QRS间期恢复正常来实现心室激动的电同步。其发生机制仍知之甚少。在这篇综述中，将讨论提出的机制及支持这些机制的证据。还将讨论证据并不完全支持的机制方面。我们还将综述直接与间接希氏束夺获的差异及生理基础，以及希氏束起搏后QRS缩窄与恢复正常的生理机制。
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