Zhang Wei, Lyman Stephen, Boutin-Foster Carla, Parks Michael L, Pan Ting-Jung, Lan Alexis, Ma Yan
Department of Epidemiology and Biostatistics, The George Washington University, Washington, DC.
Hospital for Special Surgery, New York, NY.
J Bone Joint Surg Am. 2016 Aug 3;98(15):1243-52. doi: 10.2106/JBJS.15.01009.
Previous studies of racial disparities in total joint replacement, particularly total knee arthroplasty, in the U.S. have predominantly focused on disparities between blacks and whites and were limited to Medicare patients or veterans, populations that are not representative of the entire U.S.
We sought to study racial disparities in the utilization of total knee arthroplasty, the use of high-volume hospitals, and total knee arthroplasty outcomes, including mortality and complications, using all-payer databases.
We analyzed data from 8 years and 8 racially diverse states in the State Inpatient Databases (SID). Patient race was categorized according to the SID as white, black, Hispanic, Asian, Native American, and mixed race. Both crude and adjusted racial and/or ethnic disparities were evaluated.
In comparison with whites (4.65 per 1000 population per year), black (3.90), Hispanic (3.71), Asian (3.89), Native American (4.40), and mixed-race (3.69) populations had lower rates of total knee arthroplasty utilization (p < 0.0001). After risk adjustment, the rate of total knee arthroplasty utilization was significantly lower for blacks (odds ratio [OR] = 0.87 [95% confidence interval (CI), 0.85 to 0.89]; p < 0.0001), Hispanics (OR = 0.76 [95% CI, 0.68 to 0.83]; p < 0.0001), Asians (OR = 0.83 [95% CI, 0.78 to 0.89]; p < 0.0001), Native Americans (OR = 0.87 [95% CI, 0.81 to 0.93]; p < 0.0001), and mixed race (OR = 0.84 [95% CI, 0.79 to 0.90]; p < 0.0001) compared with the rate for whites. Lower rates of total knee arthroplasty utilization for blacks, Hispanics, and mixed-race groups became worse over the years. Patients from minority groups were less likely to undergo total knee arthroplasty in high-volume hospitals than were whites. Moreover, the rates of mortality were significantly higher for blacks (OR = 1.52 [95% CI, 1.17 to 1.97]; p = 0.0017), Native Americans (OR = 6.52 [95% CI, 4.63 to 9.17]; p < 0.0001), and mixed-race patients (OR = 4.35 [95% CI, 3.24 to 5.84]; p < 0.0001). Blacks (OR = 1.08 [95% CI, 1.01 to 1.15]; p = 0.01) and mixed-race patients (OR = 1.17 [95% CI, 1.001 to 1.36]; p = 0.04) had higher rates of complications than whites.
Minorities had lower rates of total knee arthroplasty utilization but higher rates of adverse health outcomes associated with the procedure, even after adjusting for patient-related and health-care system-related characteristics. Utilization rates were based on overall population as the proportion of the population with osteoarthritis requiring arthroplasty is unknown. Future studies that consider specific patient-level information with psychosocial and behavioral factors are needed.
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
以往关于美国全关节置换(尤其是全膝关节置换)种族差异的研究主要集中在黑人和白人之间的差异,且仅限于医疗保险患者或退伍军人,这些人群并不能代表整个美国人口。
我们试图利用全付费者数据库研究全膝关节置换的使用、高容量医院的使用情况以及全膝关节置换的结果(包括死亡率和并发症)方面的种族差异。
我们分析了8个种族多样的州的州住院患者数据库(SID)中8年的数据。患者种族根据SID分为白人、黑人、西班牙裔、亚裔、美洲原住民和混血儿。评估了原始的和调整后的种族及/或族裔差异。
与白人(每年每1000人口中有4.65例)相比,黑人(3.90)、西班牙裔(3.71)、亚裔(3.89)、美洲原住民(4.40)和混血儿(3.69)人群的全膝关节置换使用率较低(p<0.0001)。经过风险调整后,黑人(优势比[OR]=0.87[95%置信区间(CI),0.85至0.89];p<0.0001)、西班牙裔(OR=0.76[95%CI,0.68至0.83];p<0.0001)、亚裔(OR=0.83[95%CI,0.78至0.89];p<0.0001)、美洲原住民(OR=0.87[95%CI,0.81至0.93];p<0.0001)和混血儿(OR=0.84[95%CI,0.79至0.90];p<0.0001)的全膝关节置换使用率与白人相比显著较低。多年来,黑人、西班牙裔和混血儿群体的全膝关节置换使用率较低的情况变得更糟。与白人相比,少数群体患者在高容量医院接受全膝关节置换的可能性较小。此外,黑人(OR=1.52[95%C,1.17至1.97];p=0.0017)、美洲原住民(OR=6.52[95%CI,4.63至9.17];p<0.0001)和混血儿患者(OR=4.35[95%CI,3.24至5.84];p<0.0001)的死亡率显著较高。黑人(OR=1.08[95%CI,1.01至1.15];p=0.01)和混血儿患者(OR=1.17[95%CI,1.001至1.36];p=0.04)的并发症发生率高于白人。
即使在调整了患者相关和医疗保健系统相关特征后,少数群体的全膝关节置换使用率较低,但与该手术相关的不良健康结果发生率较高。使用率是基于总体人群,因为需要进行关节置换的骨关节炎患者在人群中的比例未知。未来需要考虑特定患者层面信息以及心理社会和行为因素的研究。
预后水平III。有关证据水平的完整描述,请参阅作者指南。