van Alphen Nienke R, Stewart Jeremy G, Esposito Erika C, Pridgen Bryan, Gold Joseph, Auerbach Randy P
Faculty of Psychology and Neuroscience, Maastricht University, the Netherlands.
Division of Child and Adolescent Psychiatry, McLean Hospital, Belmont, Massachusetts, USA.
J Clin Psychiatry. 2017 May;78(5):592-598. doi: 10.4088/JCP.15m10326.
Presently, little is known about what factors predict adolescent psychiatric rehospitalization. Thus, the present study tested whether a battery of demographic and clinical characteristics predicted readmission within 6 months of discharge.
Participants were 165 adolescents (112 females) aged 13-19 years (mean = 15.61, SD = 1.48) admitted to an acute residential treatment program between November 25, 2013, and November 18, 2014. Patients met diagnostic criteria (DSM-IV-TR) for current major depressive disorder or dysthymia. At admission, participants completed a battery of clinical interviews and questionnaires assessing demographics, early life stress, comorbid diagnoses, psychiatric symptoms, suicidality, self-injury, and risky behavior engagement. At discharge, psychiatric symptoms were reassessed. Readmission to the same residential service was monitored over a 6-month period following discharge.
Overall, 12.1% of adolescents were rehospitalized. We conducted a series of Cox regression survival analyses to test demographic and clinical predictors of patients' time to readmission. More frequent self-injurious behaviors in the month prior to hospitalization was significantly associated with a more rapid time to rehospitalization (β = 0.05, SE = .02, Wald₁ = 4.35, P = .037, OR = 1.05, 95% CI = 1.003-1.10).
It is critical to more effectively manage self-injury during the treatment of depressed adolescents, as this is the strongest predictor of later rehospitalization.
目前,对于哪些因素可预测青少年精神科再住院情况知之甚少。因此,本研究检验了一系列人口统计学和临床特征是否能预测出院后6个月内的再次入院情况。
研究对象为2013年11月25日至2014年11月18日期间入住急性住院治疗项目的165名青少年(112名女性),年龄在13 - 19岁之间(平均 = 15.61,标准差 = 1.48)。患者符合当前重度抑郁症或心境恶劣障碍的诊断标准(《精神疾病诊断与统计手册第四版,修订版》)。入院时,参与者完成了一系列临床访谈和问卷调查,评估人口统计学、早期生活压力、共病诊断、精神症状、自杀倾向、自我伤害和危险行为参与情况。出院时,对精神症状进行重新评估。出院后6个月内监测是否再次入住同一住院服务机构。
总体而言,12.1%的青少年再次住院。我们进行了一系列Cox回归生存分析,以检验患者再次入院时间的人口统计学和临床预测因素。住院前一个月更频繁的自我伤害行为与更快的再次住院时间显著相关(β = 0.05,标准误 = 0.02,Wald₁ = 4.35,P = 0.037,比值比 = 1.05,95%置信区间 = 1.003 - 1.10)。
在治疗抑郁青少年期间更有效地管理自我伤害至关重要,因为这是后期再次住院的最强预测因素。