Halbfass Philipp, Müller Patrick, Nentwich Karin, Krug Joachim, Roos Markus, Hamm Karsten, Barth Sebastian, Szöllösi Attila, Mügge Andreas, Schieffer Bernhard, Deneke Thomas
Heart Center Bad Neustadt, Clinic for Interventional Electrophysiology, Bad Neustadt an der Saale, Germany.
University Hospital Bergmannsheil, Ruhr-University Bochum, Bochum, Germany.
Europace. 2017 Mar 1;19(3):385-391. doi: 10.1093/europace/euw070.
Oesophageal probes to monitor luminal oesophageal temperature (LET) during atrial fibrillation (AF) catheter ablation have been proposed, but their effects remain unclear. Aim of this study is to evaluate the effects of an oesophageal temperature probe with insulated thermocouples.
Patients with symptomatic, drug-refractory paroxysmal or persistent AF who underwent left atrial radiofrequency (RF) catheter ablation were prospectively enrolled. Patients were ablated using a single-tip RF contact force ablation catheter. An intraluminal oesophageal temperature probe was used in Group 1. In Group 2, patients were ablated without LET monitoring. Assessment of asymptomatic endoscopically detected oesophageal lesions (EDEL) was performed by oesophagogastroduodenoscopy (EGD) in all patients. Eighty patients (mean age 63.7 ± 10.7 years; men 56%) with symptomatic, drug-refractory paroxysmal (n = 28; 35%) or persistent AF were included. Group 1 and Group 2 patients (n = 40 in each group) were comparable in regard to baseline characteristics, but RF duration on the posterior wall was significantly shorter in Group 1 patients. Overall, seven patients (8.8%) developed EDEL (four ulcerations, three erythema). The incidence of EDEL in Group 1 and Group 2 patients was comparable (7.5 vs. 10%, P = 1.0). No major adverse events were reported in both groups.
According to these preliminary results, the use of oesophageal temperature probes with insulated thermocouples seems to be feasible in patients undergoing AF RF catheter ablation. The incidence of post-procedural EDEL when using a cut-off of 39°C is comparable to the incidence of EDEL without using a temperature probe.
已有人提出在心房颤动(AF)导管消融期间使用食管探头监测食管腔内温度(LET),但其效果仍不明确。本研究的目的是评估带有绝缘热电偶的食管温度探头的效果。
前瞻性纳入有症状、药物难治性阵发性或持续性AF且接受左心房射频(RF)导管消融的患者。使用单尖端RF接触力消融导管对患者进行消融。第1组使用腔内食管温度探头。第2组患者在无LET监测的情况下进行消融。所有患者均通过食管胃十二指肠镜检查(EGD)评估无症状内镜检测到的食管病变(EDEL)。纳入80例有症状、药物难治性阵发性(n = 28;35%)或持续性AF患者(平均年龄63.7±10.7岁;男性56%)。第1组和第2组患者(每组n = 40)在基线特征方面具有可比性,但第1组患者后壁的RF持续时间明显更短。总体而言,7例患者(8.8%)出现EDEL(4例溃疡,3例红斑)。第1组和第2组患者的EDEL发生率具有可比性(7.5%对10%,P = 1.0)。两组均未报告重大不良事件。
根据这些初步结果,在接受AF RF导管消融的患者中使用带有绝缘热电偶的食管温度探头似乎是可行的。使用39°C的阈值时,术后EDEL的发生率与未使用温度探头时EDEL的发生率相当。