使用Mirth Connect将HL7消息中的临床数据自动导入OpenClinica和tranSMART

Automated Import of Clinical Data from HL7 Messages into OpenClinica and tranSMART Using Mirth Connect.

作者信息

Camacho Rodriguez Juan Carlos, Stäubert Sebastian, Löbe Matthias

机构信息

Institute for Medical Informatics, Statistics and Epidemiology (IMISE) Leipzig University, Germany.

出版信息

Stud Health Technol Inform. 2016;228:317-21.

PMID:27577395

Abstract

Electronic data capture (EDC) tools are designed to simplify data acquisition, improving data quality and managing clinical data electronically. Some data are collected from the laboratory information management system (LIMS), which is an important data source for a study. OpenClinica is an open source clinical data management system (CDMS) for web-based electronic data capture (EDC), which is used widely in academic clinical research. TranSMART is also an open source web-based platform used for the management and analysis of different data types common in clinical and translational research. Many LIMS use the Health Level 7 standard - Version 2.x (HL7) as a message exchange protocol. In this paper, we implement Mirth Connect as a Communication Server (CS) to convert these HL7 messages either to Operational Data Model (ODM) data for the automatic import in OpenClinica or tabular-delimited text format files, whose data is uploaded in tranSMART using the tMDataLoader tool.

摘要

电子数据采集（EDC）工具旨在简化数据采集过程，提高数据质量并以电子方式管理临床数据。一些数据是从实验室信息管理系统（LIMS）收集的，LIMS是研究的重要数据源。OpenClinica是一个用于基于网络的电子数据采集（EDC）的开源临床数据管理系统（CDMS），在学术临床研究中广泛使用。TranSMART也是一个基于网络的开源平台，用于管理和分析临床及转化研究中常见的不同数据类型。许多LIMS使用健康级别7标准 - 版本2.x（HL7）作为消息交换协议。在本文中，我们实现了Mirth Connect作为通信服务器（CS），将这些HL7消息转换为用于在OpenClinica中自动导入的操作数据模型（ODM）数据或表格分隔文本格式文件，其数据使用tMDataLoader工具上传到TranSMART中。