Pontillo Maria, De Luca Maria, Pucciarini Maria Laura, Vicari Stefano, Armando Marco
Child and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Children Hospital Bambino Gesù, Rome, Italy.
Neuropsychology Unit, IRCCS Fondazione Santa Lucia, Rome, Italy.
Early Interv Psychiatry. 2018 Aug;12(4):702-707. doi: 10.1111/eip.12370. Epub 2016 Aug 31.
Recent studies have examined the prevalence of psychotic-like experiences (PLEs) and their relationship with functioning, psychopathology and distress in adult and mixed young adult and adolescent samples. There is, however, a lack of knowledge about the prevalence and clinical weight of PLEs in clinical child and adolescent (CAD) populations. Available research has primarily been conducted on community populations, and even clinical samples mostly used self-reported questionnaires. These studies also recruited participants 12 years old and older, with a consequent lack of information on children from 8 to 11 years old. We examined the prevalence of PLEs and their relationship with psychiatric diagnosis, functioning, intelligence quotient (IQ), anxiety and depressive symptoms in a clinical sample aged 8-17 years old.
The study was conducted on a clinical sample of 46 CAD with PLEs compared to a clinical sample of 60 CAD without PLEs. The two groups were compared on global, social and role functioning, IQ, anxiety and depressive symptoms, and number of psychiatric diagnoses.
Global, role and social functioning were significantly lower in the CAD clinical sample with PLEs. These significant differences were maintained when the covariate IQ, number of psychiatric diagnoses or level of anxiety or depression was added. No significant age-related differences in the presence of PLEs were found.
The findings of this study show that PLEs are common in a clinical sample of CAD, even those under 12 years old. The presence of PLEs should therefore be investigated and considered in planning treatment of non-psychotic psychiatric disorders in CAD.
近期研究调查了类精神病体验(PLEs)在成人以及青年与青少年混合样本中的发生率,及其与功能、精神病理学和痛苦之间的关系。然而,对于临床儿童和青少年(CAD)群体中PLEs的发生率和临床影响,我们尚缺乏了解。现有研究主要针对社区人群开展,即便临床样本大多使用的是自我报告问卷。这些研究招募的参与者也均为12岁及以上,因此缺乏8至11岁儿童的相关信息。我们调查了8至17岁临床样本中PLEs的发生率,及其与精神科诊断、功能、智商(IQ)、焦虑和抑郁症状之间的关系。
该研究选取了46名有PLEs的CAD临床样本,并与60名无PLEs的CAD临床样本进行对比。对两组样本在整体、社交和角色功能、智商、焦虑和抑郁症状以及精神科诊断数量方面进行了比较。
有PLEs的CAD临床样本在整体、角色和社交功能方面显著更低。当加入协变量智商、精神科诊断数量或焦虑或抑郁水平后,这些显著差异依然存在。未发现PLEs的存在与年龄有显著差异。
本研究结果表明,PLEs在CAD临床样本中很常见,即使是12岁以下的儿童。因此,在规划CAD非精神病性精神障碍的治疗时,应调查并考虑PLEs的存在情况。