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出色表现:新型一次性使用的电子输尿管镜可实现极低肾下盏进入,并可使用365μm钬激光光纤。

Impressive Performance: New Disposable Digital Ureteroscope Allows for Extreme Lower Pole Access and Use of 365 μm Holmium Laser Fiber.

作者信息

Leveillee Raymond J, Kelly Emily Fell

机构信息

Department of Urology, Florida Atlantic University , Charles E. Schmidt College of Medicine, Bethesda Hospital East, Boynton Beach, Florida.

出版信息

J Endourol Case Rep. 2016 Jun 1;2(1):114-6. doi: 10.1089/cren.2016.0051. eCollection 2016.

Abstract

BACKGROUND

Since the development of the first flexible ureteroscope, in 1964, technological advances in image quality, flexibility, and deflection have led to the development of the first single-use digital flexible ureteroscope, LithoVue™ (Boston Scientific, Marlborough, MA). With respect to reusable fiber-optic and now digital ureteroscopes, there is an initial capital cost of several thousand dollars (USD) as well as, controversy regarding durability, the cost of repairs and the burdensome reprocessing steps of ureteroscopy. The single-use LithoVue eliminates the need for costly repairs, the occurrence of unpredictable performance, and procedural delays. Renal stones located in the lower pole of the kidney can be extremely challenging as extreme deflections of greater than 160° are difficult to maintain and are often further compromised when using stone treatment tools, such as laser fibers and baskets. This case describes an initial use of the LithoVue digital disposable ureteroscope in the effective treatment of lower pole calculi using a 365 μm holmium laser fiber.

CASE REPORT

A 35-year-old female, with a medical history significant for chronic bacteriuria, and recurrent symptomatic culture proven urinary tract infections, underwent localization studies. Retrograde ureteropyelography demonstrated two calcifications adjoining, measuring a total of 1.4 cm, overlying the left renal shadow. Urine aspirated yielded clinically significant, >100,000, Escherichia coli and Streptococcus anginosus bacteriuria, which was felt to be originating from the left lower calix. This case used the newly FDA-approved LithoVue flexible disposable ureteroscope. The two stones were seen using the ureteroscope passed through an ureteral access sheath in the lower pole calix. A 365 μm holmium laser fiber was inserted into the ureteroscope and advanced toward the stones. There was no loss of deflection as the ureteroscope performed reproducibly. The laser was used for more than 4000 pulses at 15 W, producing mucoid debris and fragments. A 1.9F nitinol basket was, then, used to extract the fragments, and the patient was rendered stone free. Treatment success was confirmed by plain abdominal film obtained 1 week after stent removal.

CONCLUSION

The LithoVue system single-use digital flexible ureteroscope provides an economical advantage over both reusable digital and fiber-optic ureteroscopes. The LithoVue system uses the enhanced image resolution of the digital complementary metal oxide semiconductor imager, similar to other reusable digital ureteroscopes, while maintaining the small ureteroscope size of a flexible fiber-optic ureteroscope, allowing for consistent and effective lower pole access. Deflection characteristics are maintained even when thicker laser fibers are passed through the working channel.

摘要

背景

自1964年第一台可弯曲输尿管镜问世以来,图像质量、柔韧性和偏转方面的技术进步促使了首款一次性使用的数字式可弯曲输尿管镜LithoVue™(波士顿科学公司,马尔伯勒,马萨诸塞州)的研发。对于可重复使用的纤维光学输尿管镜以及现在的数字输尿管镜而言,初始资本成本达数千美元,并且在耐用性、维修成本以及输尿管镜检查繁琐的再处理步骤方面存在争议。一次性使用的LithoVue消除了昂贵维修的需求、不可预测性能的出现以及程序延误。位于肾下极的肾结石极具挑战性,因为大于160°的极端偏转难以维持,并且在使用激光纤维和网篮等结石治疗工具时往往会进一步受损。本病例描述了首次使用LithoVue数字式一次性输尿管镜,采用365μm钬激光纤维有效治疗肾下极结石的情况。

病例报告

一名35岁女性,有慢性菌尿病史,且反复出现经症状性培养证实的尿路感染,接受了定位检查。逆行输尿管肾盂造影显示左肾影上方有两个相邻的钙化灶,总长1.4cm。吸出的尿液培养出临床上具有显著意义的、>100,000的大肠杆菌和咽峡炎链球菌菌尿,认为其源自左肾下盏。本病例使用了新获得美国食品药品监督管理局(FDA)批准的LithoVue可弯曲一次性输尿管镜。通过输尿管进入鞘将输尿管镜插入肾下盏,观察到了这两颗结石。将一根365μm钬激光纤维插入输尿管镜并向结石推进。输尿管镜可重复操作,未出现偏转丧失。以15W功率使用激光超过4000次脉冲,产生了黏液样碎屑和结石碎片。然后使用一个1.9F镍钛合金网篮取出碎片,患者结石清除。在取出支架1周后拍摄的腹部平片证实了治疗成功。

结论

LithoVue系统一次性使用的数字式可弯曲输尿管镜相比可重复使用的数字输尿管镜和纤维光学输尿管镜具有经济优势。LithoVue系统采用了数字互补金属氧化物半导体成像仪增强的图像分辨率,与其他可重复使用的数字输尿管镜类似,同时保持了可弯曲纤维光学输尿管镜较小的尺寸,从而能够持续有效地进入肾下极。即使较粗的激光纤维通过工作通道,也能保持偏转特性。

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