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成人脊髓栓系综合征的管理:23例经验

Management of Tethered Cord Syndrome in Adults: Experience of 23 Cases.

作者信息

Sofuoglu Ozden Erhan, Abdallah Anas, Emel Erhan, Ofluoglu Ali Ender, Gunes Muslum, Guler Betul

机构信息

Bakirköy Research and Training Hospital for Neurology Neurosurgery, and Psychiatry, Department of Neurosurgery, Istanbul, Turkey.

出版信息

Turk Neurosurg. 2017;27(2):226-236. doi: 10.5137/1019-5149.JTN.15892-15.1.

Abstract

AIM

Tethered cord syndrome (TCS) is rarely diagnosed in adults. It is a complex clinicopathological entity that remains poorly understood. In this study, clinical outcomes of 23 consecutive congenital TCSs diagnosed in adults have been evaluated to establish a standard approach to treat congenital TCS diagnosed in adults.

MATERIAL AND METHODS

Medical records were retrospectively reviewed in 73 cases of TCS who were underwent surgery in our hospital, between 2005 and 2014. Cases which diagnosed and treated surgically in adults (patient age > 18 years) were included in this study.

RESULTS

Twenty-three adult cases of TCSs were treated surgically and 15 of them were female and 8 were male. The mean age was 30.3±10.7 years. The mean follow-up period was 75.6±40.5 months. The most common complaint was low back pain. The most common findings in the neurological examinations were muscular weakness and urinary incontinence. The most common co-malformations were diastematomyelia and vertebral fusion anomalies. Conus medullaris was mostly terminated at the L5 level. Detethering procedure was carried out in 87% of patients and bony septum resection without detethering was applied in 13%. Laminoplasty was performed only in 39.1%. 60.9% of patients were recovered good. 34.8% of patients were improved. The most common complication was cerebrospinal fluid leakage.

CONCLUSION

Despite the good results obtained in our surgical interventions for symptomatic TCS in adults, tethered cord releasing is complex procedure and has serious complications. Therefore, it is suggested to plan surgery according to symptoms emphasized with full neurological examination, craniospinal imaging and urodynamic tests.

摘要

目的

脊髓栓系综合征(TCS)在成人中很少被诊断出来。它是一种复杂的临床病理实体,目前仍了解不足。在本研究中,对连续23例成人先天性TCS的临床结果进行了评估,以建立治疗成人先天性TCS的标准方法。

材料与方法

回顾性分析了2005年至2014年在我院接受手术的73例TCS患者的病历。本研究纳入了在成人期(患者年龄>18岁)被诊断并接受手术治疗的病例。

结果

23例成人TCS患者接受了手术治疗,其中15例为女性,8例为男性。平均年龄为30.3±10.7岁。平均随访期为75.6±40.5个月。最常见的主诉是腰痛。神经检查中最常见的发现是肌肉无力和尿失禁。最常见的合并畸形是脊髓纵裂和椎体融合异常。脊髓圆锥大多终止于L5水平。87%的患者进行了脊髓松解术,13%的患者进行了无脊髓松解的骨隔切除术。仅39.1%的患者进行了椎板成形术。60.9%的患者恢复良好。34.8%的患者有所改善。最常见的并发症是脑脊液漏。

结论

尽管我们对有症状的成人TCS进行手术干预取得了良好的效果,但脊髓松解是一个复杂的手术,且有严重的并发症。因此,建议根据全面的神经检查、颅脊髓成像和尿动力学检查所强调的症状来规划手术。

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