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耶和华见证会患者成功进行无输血胰切除术。

Successful transfusion-free pancreatectomy in Jehovah's Witness patients.

作者信息

Lee Jong Oh, Kim Dong Won, Jeong Mi Ae, Lee Hee Jong, Kim Kyu Nam, Choi Dongho

机构信息

Department of Surgery, Hanyang University College of Medicine, Seoul, Korea.

Department of Anesthesiology and Pain Medicine, Hanyang University College of Medicine, Seoul, Korea.

出版信息

Korean J Hepatobiliary Pancreat Surg. 2016 Aug;20(3):121-6. doi: 10.14701/kjhbps.2016.20.3.121. Epub 2016 Aug 29.

Abstract

BACKGROUNDS/AIMS: Although perioperative therapies have improved greatly, pancreatectomies still often need blood transfusions. However, the morbidity from blood transfusions, the poor prognosis of blood transfused patients, high cost, and decreasing supply of blood products is accelerating transfusion-free (TF) surgery in the patients who have pacreatectomies. The aim of this study was to assess the feasibility of TF pancreatectomies for patients who are Jehovah's Witness.

METHODS

We investigated the possibility of TF pancreatectomies for the Jehovah's Witness patients undergoing pancreatectomies between January 2007 and Februay 2014. There were 4 cases of Whipple's operation, 4 of pylorus-preserving pancreaticoduodenectomy, 2 of radical antegrade modular pancreatosplenectomy and 1 of laparoscopic distal pancreatectomy. All were performed by one surgeon.

RESULTS

Most of the TF pancreatecomies patients received perioperative blood augmentation and intraoperative acute normovolemic hemodilution (ANH). They received no blood transfusions at any time during their hospitalization, and pre- and intra-operative data and outcomes were acceptably favorable.

CONCLUSIONS

To the best of our knowledge, this report is the first successful consecutive pancreatectomy program for Jehovah's Witness not involving blood transfusion. TF pancreatectomy can be performed successfully in selected Jehovah's Witness. Postoperative prognosis and outcomes should be confirmed in follow up studies.

摘要

背景/目的:尽管围手术期治疗已取得很大进展,但胰腺切除术仍常常需要输血。然而,输血的发病率、输血患者的不良预后、高成本以及血液制品供应的减少,促使在胰腺切除患者中开展无输血(TF)手术。本研究的目的是评估为耶和华见证会信徒实施TF胰腺切除术的可行性。

方法

我们调查了2007年1月至2014年2月期间接受胰腺切除术的耶和华见证会信徒患者实施TF胰腺切除术的可能性。其中有4例Whipple手术、4例保留幽门的胰十二指肠切除术、2例根治性顺行模块化胰脾切除术和1例腹腔镜远端胰腺切除术。所有手术均由一名外科医生完成。

结果

大多数TF胰腺切除患者接受了围手术期血液扩容和术中急性等容血液稀释(ANH)。他们在住院期间任何时候都未输血,术前和术中数据及结果均令人满意。

结论

据我们所知,本报告是首例为耶和华见证会信徒成功实施的连续不涉及输血的胰腺切除手术。TF胰腺切除术可在选定的耶和华见证会信徒中成功实施。术后预后和结果应在后续研究中得到证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3272/5018948/8a2b3dc60bbb/kjhbps-20-121-g001.jpg

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