Park Keun Young, Kim Byung Moon, Kim Dong Joon
Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.; Severance Hospital Stroke Center, Yonsei University College of Medicine, Seoul, Korea.
Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.; Severance Hospital Stroke Center, Yonsei University College of Medicine, Seoul, Korea.
Neurointervention. 2016 Sep;11(2):99-104. doi: 10.5469/neuroint.2016.11.2.99. Epub 2016 Sep 3.
To compare clinical and angiographic outcomes between balloon-assisted (BAC) and stent-assisted coiling for internal carotid artery unruptured aneurysms (ICA-UA).
A total of 227 ICA-UA in 190 patients were treated with BAC (120 patients, 141 ICA-UA) or SAC (70 patients, 86 ICA-UA. We compared characteristics of patients and ICA-UA, and clinical and angiographic outcomes between groups.
Aneurysm size and neck diameter were greater for SAC than in BAC, but aneurysm volume and coil packing density were not different between groups. Immediate angiographic occlusion grade was better for BAC than for SAC. Periprocedural thromboembolic events were more frequent during SAC (11.6%) than BAC (2.4%) per aneurysm, but hemorrhagic events were the opposite (2.4% for BAC and none for SAC per aneurysm) (p < 0.05). At discharge, treatment-related morbi-mortality rates were 1.6% for BAC and 1.4% per patient for SAC. At clinical follow-up (BAC, 118 patients [98.3%] for a mean of 48.4 months; SAC, 69 patients [98.6%], for a mean of 37.4 months), 1 additional treatment-related infarction occurred during SAC, resulting in a modified Rankin scale score of 4. Thus, overall treatment-related morbi-mortality rates were 1.7% in BAC and 2.9% in SAC. At imaging follow-up (BAC, 135 aneurysms [95.7%] for 28.3 months; SAC, 81 aneurysms [94.1%] for 23.9 months), BAC and SAC showed stable or improved occlusion in 94.1% and 95.0%, minor recurrence in 4.4% and 2.5%, and major recurrence in 1.5% and 2.5%, respectively.
Both BAC and SAC were safe and effective techniques for ICA-UA. There were no differences in morbi-mortality and recurrence rates between groups.
比较球囊辅助(BAC)和支架辅助弹簧圈栓塞术治疗颈内动脉未破裂动脉瘤(ICA-UA)的临床和血管造影结果。
190例患者共227个ICA-UA接受了BAC治疗(120例患者,141个ICA-UA)或SAC治疗(70例患者,86个ICA-UA)。我们比较了患者和ICA-UA的特征,以及两组之间的临床和血管造影结果。
SAC组的动脉瘤大小和颈部直径大于BAC组,但两组之间的动脉瘤体积和弹簧圈填充密度无差异。BAC组的即刻血管造影闭塞分级优于SAC组。每个动脉瘤围手术期血栓栓塞事件在SAC组(11.6%)比BAC组(2.4%)更频繁,但出血事件则相反(BAC组每个动脉瘤为2.4%,SAC组无)(p<0.05)。出院时,BAC组的治疗相关病死亡率为1.6%,SAC组为1.4%。临床随访时(BAC组,118例患者[98.3%],平均48.4个月;SAC组,69例患者[98.6%],平均37.4个月),SAC组发生1例额外的治疗相关梗死,改良Rankin量表评分为4分。因此,BAC组的总体治疗相关病死亡率为1.7%,SAC组为2.9%。影像学随访时(BAC组,135个动脉瘤[95.7%],随访28.3个月;SAC组,81个动脉瘤[94.1%],随访23.9个月),BAC组和SAC组的闭塞稳定或改善率分别为94.1%和95.0%,轻微复发率分别为4.4%和2.5%,严重复发率分别为1.5%和2.5%。
BAC和SAC都是治疗ICA-UA的安全有效技术。两组之间的病死亡率和复发率无差异。