Karatolios Konstantinos, Rolfes Caroline, Wulf Hinnerk, Schieffer Bernhard
Universitätsklinikum Marburg, Klinik für Kardiologie, internistische Intensivmedizin und Angiologie.
Universitätsklinikum Marburg, Klinik für Anästhesie und Intensivtherapie.
Anasthesiol Intensivmed Notfallmed Schmerzther. 2016 Sep;51(9):518-25. doi: 10.1055/s-0042-102145. Epub 2016 Sep 15.
Cardiovascular complications, particularly perioperative myocardial infarction (PMI), are major contributors to mortaliyt after noncardiac surgery. PMI often occurs unnoticed without symptoms or ECG changes. Despite ist silent presentation, PMI is associated with increased mortality. The combination of high associated mortality and diagnostic challenges mandates increased awareness of PMI. Perioperative myocardial infarction may result from plaque rupture (PMI type I) or be caused by a myocardial supply-demand imbalance of oxygen without plaque rupture (PMI type II). Most PMIs occur within the first 3 days after surgery, highlighting the need for clinical monitoring in order to allow fast diagnosis and initiation of appropriate therapy. Measurement of cardiac troponin and 12-lead ECG are the diagnostic cornerstone. Therapy of PMI represents a challenge for physicians and requires a collaboration of surgeons, anesthesiologists and cardiologists.
心血管并发症,尤其是围手术期心肌梗死(PMI),是非心脏手术后死亡的主要原因。PMI常无明显症状或心电图改变而未被察觉。尽管其表现隐匿,但PMI与死亡率增加相关。高相关死亡率和诊断挑战的结合要求提高对PMI的认识。围手术期心肌梗死可能由斑块破裂(I型PMI)引起,或由无斑块破裂的心肌氧供需失衡导致(II型PMI)。大多数PMI发生在术后的前3天内,这凸显了临床监测的必要性,以便能够快速诊断并启动适当治疗。心肌肌钙蛋白测定和12导联心电图是诊断的基石。PMI的治疗对医生来说是一项挑战,需要外科医生、麻醉师和心脏病专家的协作。