Department of Cardiovascular Surgery, Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.
Department of Cardiovascular Surgery, Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.
J Thorac Cardiovasc Surg. 2016 Oct;152(4):1019-28. doi: 10.1016/j.jtcvs.2016.06.058. Epub 2016 Jul 28.
Aortic valve replacement (AVR) in patients with a small aortic annulus is a challenging problem. The objective of this study was to compare 4 surgical approaches in terms of hemodynamics and perioperative outcomes.
A retrospective single-center study included 351 consecutive patients with a small aortic annulus (≤21 mm) who underwent aortic valve surgery between January 2007 and December 2014. Surgical techniques included standard AVR in 259 (74%) patients, aortic root enlargement in 20 (6%), implantation of a stentless bioprosthesis in 23 (6%), and sutureless AVR in 49 (13%).
Three hundred and eleven (89%) patients were female. The mean Logistic EuroSCORE II varied significantly among the groups and ranged from 6.5% ± 5.4% in the standard AVR group to 9.2% ± 4.7% in the stentless group. Early mortality occurred in 26 (7%) patients. Patients in the stentless group had the lowest aortic valve mean gradients on predischarge transthoracic echocardiography (10.9 ± 6.2 mm Hg; P < .001). In the stented group, the Trifecta prosthesis displayed the lowest postoperative mean transaortic gradient (10.3 ± 3.6; P < .001) with no severe prosthesis-patient mismatch. Postoperative gradients of the sutureless group were comparable with stented prostheses.
In our study, stentless AVR and Trifecta bioprostheses had the best hemodynamic outcomes. The Perceval sutureless prosthesis provides reasonable hemodynamic performance and is a safe alternative.
主动脉瓣置换术(AVR)在小主动脉瓣环患者中是一个具有挑战性的问题。本研究的目的是比较 4 种手术方法在血流动力学和围手术期结果方面的差异。
回顾性单中心研究纳入了 2007 年 1 月至 2014 年 12 月期间接受主动脉瓣手术的 351 例小主动脉瓣环(≤21mm)连续患者。手术技术包括 259 例(74%)标准 AVR、20 例(6%)主动脉根部扩大、23 例(6%)植入无支架生物瓣和 49 例(13%)无缝线 AVR。
311 例(89%)患者为女性。各组间 Logistic EuroSCORE II 差异显著,标准 AVR 组为 6.5%±5.4%,无支架组为 9.2%±4.7%。26 例(7%)患者早期死亡。出院前经胸超声心动图显示无支架组主动脉瓣平均梯度最低(10.9±6.2mmHg;P<.001)。在支架组中,Trifecta 假体术后平均跨瓣梯度最低(10.3±3.6;P<.001),且无严重假体-患者不匹配。无缝线组术后梯度与支架假体相当。
在本研究中,无支架 AVR 和 Trifecta 生物瓣具有最佳的血流动力学结果。Perceval 无缝线假体提供了合理的血流动力学性能,是一种安全的替代方法。