Pyykkö I, Koskimies K, Starck J, Pekkarinen J, Färkkilä M, Inaba R
Department of Otolaryngology, University Hospital of Helsinki, Finland.
Br J Ind Med. 1989 Jul;46(7):439-46. doi: 10.1136/oem.46.7.439.
A detailed analysis of risk factors for the development of sensorineural hearing loss (SNHL) was carried out in 199 forest workers. The hearing threshold of both ears at 4000 Hz was measured, and the effect of age, exposure to noise, blood pressure, presence of vibration induced white finger (VWF), tobacco smoking, plasma LDL-cholesterol concentration, and consumption of drugs were evaluated by multiple linear regression analysis. Aging was the major risk factor, followed by exposure to occupational noise and the presence of VWF. Plasma LDL-cholesterol concentration and the use of antihypertensive drugs also correlated significantly with SNHL. These main factors were able to explain about 28% of the SNHL variance. Additional factors in the analysis, including smoking, systolic and diastolic blood pressure, and consumption of salicylates did not significantly contribute to the genesis of SNHL.
对199名林业工人进行了感音神经性听力损失(SNHL)发生风险因素的详细分析。测量了4000Hz时双耳的听力阈值,并通过多元线性回归分析评估了年龄、噪声暴露、血压、振动性白指(VWF)的存在、吸烟、血浆低密度脂蛋白胆固醇浓度和药物使用的影响。衰老为主要风险因素,其次是职业噪声暴露和VWF的存在。血浆低密度脂蛋白胆固醇浓度和抗高血压药物的使用也与SNHL显著相关。这些主要因素能够解释约28%的SNHL方差。分析中的其他因素,包括吸烟、收缩压和舒张压以及水杨酸盐的使用,对SNHL的发生没有显著影响。