Ciglar Mirta, Bjedov Sarah, Maleković Hrvoje
University of Zagreb, School of Medicine, Šalata 3, 10 000 Zagreb, Croatia,
Psychiatr Danub. 2016 Sep;28(3):273-277.
Despite many advantages of long-acting injectable antipsychotics (LAIA), this type of therapy is still underused in routine practice. Since psychiatrists' attitudes play an important role in prescription rate of LAIA, we found it valuable to examine their attitudes because, according to our knowledge, there hasn't been similar research in Croatia so far.
In this research, we included the total of 48 psychiatrists. For research purposes, we created a questionnaire modeled on standardized questionnaire. Results are described with descriptive statistics and Likert scale was used to measure respondents' attitudes to statements.
The number of years of their experience in practice is expressed with median of 13.50 years with minimal value of 1.00 and maximum value of 36.00 years. Most of psychiatrists find that LAIA play an important role in treatment of schizophrenia (n=44, 93.62%) and that they tend to prescribe that type of therapy (n=39, 81.25%). Almost all of psychiatrists (n=45, 93.75%) agree or strongly agree that it is easier to control patients' disease if they are treated with LAIA rather than with oral therapy and 32 of them (68.08%) think that doctor-patient relationship is more successful when patients are treated with LAIA than with oral antipsychotics. According to their experience (n=32, 68.08%) patients prefer to be treated with oral antipsychotics instead of LAIA. We expressed approximate percentage of their patients treated with LAIA with median of 20%, with minimum value of 0.00% and maximum value of 70.00%.
According to the results of our research, attitudes of psychiatrists towards LAIA are mostly positive, but considering the fact that there is a small number of their patients who are treated with them, we emphasize that psychiatrists still prescribe oral antipsychotics much more often than LAIA. Despite positive attitudes of patients towards LAIA, majority of psychiatrists think that patients would rather choose oral therapy.
尽管长效注射用抗精神病药物(LAIA)有诸多优势,但这类疗法在常规临床实践中的应用仍未得到充分利用。由于精神科医生的态度在LAIA的处方率中起着重要作用,我们认为研究他们的态度很有价值,因为据我们所知,克罗地亚目前尚未有类似研究。
本研究共纳入48名精神科医生。为进行研究,我们以标准化问卷为蓝本设计了一份调查问卷。结果采用描述性统计进行描述,并用李克特量表来衡量受访者对各陈述的态度。
他们的临床实践年限中位数为13.50年,最小值为1.00年,最大值为36.00年。大多数精神科医生认为LAIA在精神分裂症治疗中发挥着重要作用(n = 44,93.62%),并且他们倾向于开具这类疗法的处方(n = 39,81.25%)。几乎所有精神科医生(n = 45,93.75%)同意或强烈同意,与口服疗法相比,使用LAIA治疗更容易控制患者的病情,其中32人(68.08%)认为患者接受LAIA治疗时医患关系比使用口服抗精神病药物时更融洽。根据他们的经验(n = 32,68.08%),患者更倾向于接受口服抗精神病药物治疗而非LAIA。我们用中位数20%来表示接受LAIA治疗的患者的大致比例,最小值为0.00%,最大值为70.00%。
根据我们的研究结果,精神科医生对LAIA的态度大多是积极的,但考虑到接受这类治疗的患者数量较少这一事实,我们强调精神科医生开具口服抗精神病药物的频率仍远高于LAIA。尽管患者对LAIA持积极态度,但大多数精神科医生认为患者更愿意选择口服疗法。