克罗地亚重症精神疾病患者对长效注射用抗精神病药物的态度。

Attitudes of Croatian patients with severe mental illness towards long-acting injectable antipsychotics.

作者信息

Bjedov Sarah, Ciglar Mirta, Maleković Hrvoje

机构信息

University of Zagreb, School of Medicine, Šalata 3, 10 000 Zagreb, Croatia,

出版信息

Psychiatr Danub. 2016 Sep;28(3):278-283.

PMID:27658837

Abstract

BACKGROUND

It has been shown that patients' attitudes towards long-acting injectable antipsychotics (LAIA) have the influence on the acceptance and use of this type of therapy. The aim of our study was to explore attitudes of patients because, according to our knowledge, there has been no similar research in Croatia thus far.

SUBJECTS AND METHODS

Two questionnaires were given to the total of 100 patients, the first one to patients treated with LAIA (group 1) and the second one to patients treated with oral antipsychotics (group 2).

RESULTS

Significantly more patients treated with LAIA find that good aspects of their medication outweigh the bad (p=0.014). Almost one third of patients treated with oral antipsychotics (n=16, 32%) quit taking medication when they feel better and 6 patients (12%) very often or often forget to take medication. Larger number of patients treated with LAIA feels much better since they have been taking their medication (group 1=82%, group 2=68%). Almost all patients treated with LAIA would recommend their therapy to other patients (92%), which is not the case with patients treated with oral antipsychotics (58%). 90% of patients decided to take LAIA because of suggestion given by their psychiatrists and 10% were persuaded by their psychiatrists. When given potential advantages of LAIA, 84% of patients said they found very positive the fact that they didn't have to think about taking their medication every day, 82% were fond of LAIA's simplicity, 68% considered positive that their psychiatrists had better control over their treatment and 66% were very content with their recovery.

CONCLUSION

The larger number of patients treated with LAIA is content with their therapy than patients treated with oral antipsychotics. Patients' attitudes have changed in a way that they don't find LAIA coercive anymore and most of them agreed to that type of therapy on a suggestion given by their psychiatrists.

摘要

背景

已有研究表明，患者对长效注射用抗精神病药物（LAIA）的态度会影响此类疗法的接受和使用情况。我们研究的目的是探究患者的态度，因为据我们所知，克罗地亚迄今为止尚未开展过类似研究。

对象与方法

共向100名患者发放了两份问卷，第一份发给接受LAIA治疗的患者（第1组），第二份发给接受口服抗精神病药物治疗的患者（第2组）。

结果

接受LAIA治疗的患者中，认为药物疗效利大于弊的人数显著更多（p = 0.014）。近三分之一接受口服抗精神病药物治疗的患者（n = 16，32%）感觉病情好转后便停药，6名患者（12%）经常或非常频繁地忘记服药。接受LAIA治疗的患者中，更多人表示服药后感觉好多了（第1组 = 82%，第2组 = 68%）。几乎所有接受LAIA治疗的患者都会向其他患者推荐这种疗法（92%），而接受口服抗精神病药物治疗的患者则不然（58%）。90%的患者因精神科医生的建议而决定接受LAIA治疗，10%是被精神科医生说服的。当被告知LAIA的潜在优势时，84%的患者表示他们认为不必每天想着服药这一点非常积极，82%喜欢LAIA的简便性，68%认为精神科医生能更好地控制他们的治疗是积极的，66%对自己的康复非常满意。