Howard George, Safford Monika M, Moy Claudia S, Howard Virginia J, Kleindorfer Dawn O, Unverzagt Fredrick W, Soliman Elsayed Z, Flaherty Matthew L, McClure Leslie A, Lackland Daniel T, Wadley Virginia G, Pulley LeaVonne, Cushman Mary
Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Division of General Internal Medicine, Weill Cornell Medical College, New York, New York.
J Am Geriatr Soc. 2017 Jan;65(1):83-90. doi: 10.1111/jgs.14472. Epub 2016 Sep 26.
To describe the incidence of cardiovascular risk factors, or race-related disparities in incidence, across the age spectrum in adults.
Longitudinal cohort.
National sample.
Community-dwelling black and white adults recruited between 2003 and 2007.
Incident hypertension, diabetes mellitus, dyslipidemia and atrial fibrillation over 10 years of follow-up in 10,801 adults, stratified according to age (45-54, 55-64, 65-74, ≥75).
There was no evidence (P ≥ .68) of an age-related difference in the incidence of hypertension for white men (average incidence 38%), black men (48%), or black women (54%), although for white women incidence increased with age (45-54, 27%; ≥75, 40%). Incidence of diabetes mellitus was lower at older ages for white men (45-54, 15%; ≥75, 8%), black men (45-54, 29%; ≥75, 13%), and white women (45-54, 11%; ≥75, 4%), although there was no evidence (P = .11) of age-related changes for black women (average incidence 21%). For dyslipidemia, incidence for all race-sex groups was approximately 20% for aged 45 to 54 but approximately 30% for aged 54 to 64 and 65 to 74 and approximately 22% for aged 75 and older. Incidence of atrial fibrillation was low at age 45 to 54 (<5%) but for aged 75 and older was approximately 20% for whites and 11% for blacks. The incidence of hypertension, diabetes mellitus, and dyslipidemia was higher in blacks across the age spectrum but lower for atrial fibrillation.
Incidence of risk factors remains high in older adults. Blacks have a higher incidence of hypertension, diabetes mellitus, and dyslipidemia after age 45, underscoring the ongoing importance of prevention of all three conditions in mid- to later life.
描述成年人群体中各年龄段心血管危险因素的发生率,或发生率方面与种族相关的差异。
纵向队列研究。
全国性样本。
2003年至2007年间招募的社区居住的黑人和白人成年人。
对10801名成年人进行10年随访期间的新发高血压、糖尿病、血脂异常和心房颤动情况,按年龄分层(45 - 54岁、55 - 64岁、65 - 74岁、≥75岁)。
白人男性(平均发生率38%)、黑人男性(48%)或黑人女性(54%)的高血压发生率均无年龄相关差异的证据(P≥0.68),不过白人女性的发生率随年龄增加(45 - 54岁,27%;≥75岁,40%)。白人男性(45 - 54岁,15%;≥75岁,8%)、黑人男性(45 - 54岁,29%;≥75岁,13%)和白人女性(45 - 54岁,11%;≥75岁,4%)在较高年龄时糖尿病发生率较低,不过黑人女性无年龄相关变化的证据(平均发生率21%,P = 0.11)。对于血脂异常,45至54岁所有种族 - 性别人群的发生率约为20%,54至64岁和65至74岁约为30%,75岁及以上约为22%。心房颤动的发生率在45至54岁时较低(<5%),但在75岁及以上时,白人约为20%,黑人约为11%。高血压、糖尿病和血脂异常的发生率在各年龄段黑人中均较高,但心房颤动发生率较低。
老年人危险因素的发生率仍然很高。45岁以后,黑人患高血压、糖尿病和血脂异常的发生率更高,这突出了在中年及老年预防这三种疾病的持续重要性。