Vutcovici Maria, Brassard Paul, Bitton Alain
Maria Vutcovici, Alain Bitton, Division of Gastroenterology, McGill University Health Centre, Montreal General Hospital, Montreal, Québec H3G 1A4, Canada.
World J Gastroenterol. 2016 Sep 14;22(34):7735-41. doi: 10.3748/wjg.v22.i34.7735.
Airway diseases are the most commonly described lung manifestations of inflammatory bowel disease (IBD). However, the similarities in disease pathogenesis and the sharing of important environmental risk factors and genetic susceptibility suggest that there is a complex interplay between IBD and airway diseases. Recent evidence of IBD occurrence among patients with airway diseases and the higher than estimated prevalence of subclinical airway injuries among IBD patients support the hypothesis of a two-way association. Future research efforts should be directed toward further exploration of this association, as airway diseases are highly prevalent conditions with a substantial public health impact.
气道疾病是炎症性肠病(IBD)最常描述的肺部表现。然而,疾病发病机制的相似性以及重要环境风险因素和遗传易感性的共享表明,IBD与气道疾病之间存在复杂的相互作用。气道疾病患者中IBD发生的最新证据以及IBD患者中亚临床气道损伤的患病率高于预期,支持了双向关联的假设。未来的研究工作应致力于进一步探索这种关联,因为气道疾病是具有重大公共卫生影响的高度流行疾病。