Korkmaz Serdal, Kulakoglu Sinan, Gorkem Hasan, Aygun Bilal, Cetinkaya Ali
Associated Professor Serdal Korkmaz MD, Division of Hematology,, Kayseri Education and Research Hospital 38100,, Kayseri, Turkey, T: +90 352 336 88 84,, Fax: +90 352 320 73 13,
Ann Saudi Med. 2016 Sep-Oct;36(5):364-366. doi: 10.5144/0256-4947.2016.364.
Polycythemia vera is a Philadelphia chromosome-negative myeloproliferative neoplasm. Chronic lymphocytic leukemia is a monoclonal expansion of a CD5+ CD19+ B lymphocytes. Chronic myeloproliferative neoplasms may coexist with indolent B-cell malignant lymphomas of various types. The association of chronic lymphocytic leukemia with polycythemia vera is a rare event with only a few cases of coexistence ever reported. We report a 56-year-old man in whom these two disorders were diagnosed concomitantly. Possible etiopathogenic relationships between both disorders are discussed in this case report.
真性红细胞增多症是一种费城染色体阴性的骨髓增殖性肿瘤。慢性淋巴细胞白血病是CD5+CD19+B淋巴细胞的单克隆扩增。慢性骨髓增殖性肿瘤可能与各种类型的惰性B细胞恶性淋巴瘤共存。慢性淋巴细胞白血病与真性红细胞增多症的关联是罕见事件,仅有少数共存病例的报道。我们报告一名56岁男性,其同时被诊断患有这两种疾病。本病例报告讨论了这两种疾病之间可能的病因关系。
6例。