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慢性淋巴细胞白血病与真性红细胞增多症并存:一例报告并文献复习

Coexistence of chronic lymphocytic leukemia and polycythemia vera: a case report and review of the literature.

作者信息

Korkmaz Serdal, Kulakoglu Sinan, Gorkem Hasan, Aygun Bilal, Cetinkaya Ali

机构信息

Associated Professor Serdal Korkmaz MD, Division of Hematology,, Kayseri Education and Research Hospital 38100,, Kayseri, Turkey, T: +90 352 336 88 84,, Fax: +90 352 320 73 13,

出版信息

Ann Saudi Med. 2016 Sep-Oct;36(5):364-366. doi: 10.5144/0256-4947.2016.364.

Abstract

UNLABELLED

Polycythemia vera is a Philadelphia chromosome-negative myeloproliferative neoplasm. Chronic lymphocytic leukemia is a monoclonal expansion of a CD5+ CD19+ B lymphocytes. Chronic myeloproliferative neoplasms may coexist with indolent B-cell malignant lymphomas of various types. The association of chronic lymphocytic leukemia with polycythemia vera is a rare event with only a few cases of coexistence ever reported. We report a 56-year-old man in whom these two disorders were diagnosed concomitantly. Possible etiopathogenic relationships between both disorders are discussed in this case report.

SIMILAR CASES PUBLISHED

摘要

未标记

真性红细胞增多症是一种费城染色体阴性的骨髓增殖性肿瘤。慢性淋巴细胞白血病是CD5+CD19+B淋巴细胞的单克隆扩增。慢性骨髓增殖性肿瘤可能与各种类型的惰性B细胞恶性淋巴瘤共存。慢性淋巴细胞白血病与真性红细胞增多症的关联是罕见事件,仅有少数共存病例的报道。我们报告一名56岁男性,其同时被诊断患有这两种疾病。本病例报告讨论了这两种疾病之间可能的病因关系。

已发表的类似病例

6例。

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