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原发和继发 Furlow 腭裂修复术后的腭部运动

Palatal Motion After Primary and Secondary Furlow Palatoplasty.

机构信息

Tufts University School of Medicine, Boston, Massachusetts.

Tufts University School of Medicine, Boston, Massachusetts2Department of Otolaryngology-Head and Neck Surgery, Tufts Medical Center, Boston, Massachusetts.

出版信息

JAMA Otolaryngol Head Neck Surg. 2017 Feb 1;143(2):111-115. doi: 10.1001/jamaoto.2016.2783.

Abstract

IMPORTANCE

Indications for Furlow palatoplasty include primary repair of cleft palate as well as secondary repair, or secondary palatoplasty for treatment of velopharyngeal insufficiency. Speculation exists surrounding the benefit of secondary Furlow palatoplasty in cases of a previously well-reconstructed palate or a short but otherwise anatomically normal soft palate because it has been theorized that reorientation of a previously reconstructed or normal muscular levator sling should in fact worsen palatal motion.

OBJECTIVE

To compare palatal motion following primary and secondary Furlow palatoplasty using footage from postoperative nasopharyngoscopy videos.

DESIGN, SETTING, AND PARTICIPANTS: In this retrospective case series, medical records in a database of an urban academic pediatric otolaryngology practice was used to identify patients who had undergone either primary or secondary Furlow palatoplasty. Subjects with adequate postoperative nasopharyngoscopy footage were randomized, and 2 blinded reviewers assessed soft palate motion in each video using an abbreviated version of the Golding-Kushner scale.

MAIN OUTCOMES AND MEASURES

Reviewers' blinded ratings of soft palate motion were quantified using a modified Golding-Kushner scale to generate a mean palatal motion score for each subject (range, 0.0-2.0). Scores of primary and secondary Furlow palatoplasty patients were compared.

RESULTS

Over a 4-year period, 20 patients with adequate postoperative nasopharyngoscopy footage were identified (12 primary Furlow palatoplasty patients and 8 secondary Furlow palatoplasty patients). Patients consisted of 8 males and 12 females and ranged in age from 12 months to 22 years at the time of postoperative nasopharyngoscopy. Modified Golding-Kushner scores were similar between groups: mean primary group, 1.61 (range, 0.5-2.0); mean secondary group, 1.53 (range, 0.75-2.0); absolute difference in mean, 0.08 (95% CI, 0.00-0.43); effect size, Hedges g, 0.18. There was fair interrater reliability (interclass coefficient, R = 0.45), consistent with prior reports using this scale. No significant difference in postoperative palatal motion scores was identified between primary and secondary palatoplasty groups in this study.

CONCLUSIONS AND RELEVANCE

When examined in isolation, postoperative motion of the soft palate appears similar following both primary and secondary Furlow palatoplasty procedures, suggesting that there are no major deleterious effects on palatal motion following secondary Furlow palatoplasty.

摘要

重要性

Furlow 腭裂修补术的适应证包括腭裂的初次修复以及治疗腭咽闭合不全的二次修复或二次腭裂修补术。有人推测,对于先前重建良好的腭部或软腭较短但解剖结构正常的病例,二次 Furlow 腭裂修补术的益处在于,先前重建或正常的肌肉提肌吊带的重新定向实际上会恶化腭部运动,因此,对于先前重建或正常的肌肉提肌吊带的重新定向实际上会恶化腭部运动。

目的

使用术后鼻咽镜录像比较初次和二次 Furlow 腭裂修补术后的腭部运动。

设计、设置和参与者:在这项回顾性病例系列研究中,使用城市学术小儿耳鼻喉科实践数据库中的病历来确定接受初次或二次 Furlow 腭裂修补术的患者。对术后鼻咽镜录像有足够资料的受试者进行随机分组,由 2 名盲法评审员使用 Golding-Kushner 量表的简化版评估每个视频中的软腭运动。

主要结果和措施

使用改良的 Golding-Kushner 量表对评审员的盲法评分进行量化,为每位受试者生成一个平均腭部运动评分(范围,0.0-2.0)。比较初次和二次 Furlow 腭裂修补术患者的评分。

结果

在 4 年期间,确定了 20 名有足够术后鼻咽镜录像资料的患者(12 名初次 Furlow 腭裂修补术患者和 8 名二次 Furlow 腭裂修补术患者)。患者包括 8 名男性和 12 名女性,在术后鼻咽镜检查时年龄从 12 个月到 22 岁不等。两组的改良 Golding-Kushner 评分相似:初次组平均 1.61(范围,0.5-2.0);二次组平均 1.53(范围,0.75-2.0);平均差值,0.08(95%CI,0.00-0.43);效应量,Hedges g,0.18。有良好的组内可靠性(组间等级相关系数,R=0.45),与该量表的先前报告一致。在这项研究中,初次和二次腭裂修补术后,软腭的术后运动评分无显著差异。

结论和相关性

单独检查时,初次和二次 Furlow 腭裂修补术后软腭的运动似乎相似,表明二次 Furlow 腭裂修补术后对腭部运动没有重大的不良影响。

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