Falland-Cheung Lisa, Waddell J Neil, Lazarjan Milad Soltanipour, Jermy Mark C, Winter Taylor, Tong Darryl, Brunton Paul A
Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, PO Box 647, Dunedin 9054, New Zealand.
Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, PO Box 647, Dunedin 9054, New Zealand.
J Mech Behav Biomed Mater. 2017 Jan;65:665-671. doi: 10.1016/j.jmbbm.2016.09.034. Epub 2016 Sep 28.
The suitability of agar/glycerol/water and agar/glycerol mixtures as brain simulants was investigated. Test specimens (n=15) (50x27×37mm) were fabricated for these different mixtures and conditioned to 12°C, 22°C, and 26°C prior to testing. For comparison, fresh deer brain specimens (n=20) were sourced and prepared to the same dimensions as the agar/glycerol(/water) mixtures and conditioned to 12°C and 37°C. High impact tests were carried out with a 0.22-caliber air rifle pellet and a high-speed camera was used to record the projectile as it passed through the specimens, allowing for energy loss and vertical displacement velocity calculation. Although the agar/glycerol/water mixture presented with similar vertical expansion and contraction of the specimens to the warm and cold deer brains, a two-fold decrease of the vertical expansion and contraction was noticed with the agar/glycerol specimens. Also considerably less extrusion of this mixture out of the exit and entry sides after specimen penetration was observed. Of the simulants tested, agar/glycerol/water was the most suitable brain simulant for ballistic testing and impact studies.
研究了琼脂/甘油/水和琼脂/甘油混合物作为脑模拟物的适用性。针对这些不同的混合物制作了测试样本(n = 15)(50×27×37mm),并在测试前将其调节至12°C、22°C和26°C。为作比较,获取了新鲜鹿脑样本(n = 20),并将其制备成与琼脂/甘油(/水)混合物相同的尺寸,调节至12°C和37°C。使用0.22口径气步枪子弹进行了高冲击测试,并使用高速相机记录子弹穿过样本的过程,以便计算能量损失和垂直位移速度。尽管琼脂/甘油/水混合物在样本的垂直膨胀和收缩方面与温热和冷的鹿脑相似,但琼脂/甘油样本的垂直膨胀和收缩减少了两倍。在样本穿透后,还观察到该混合物从出口和入口侧挤出的情况明显减少。在所测试的模拟物中,琼脂/甘油/水是最适合用于弹道测试和冲击研究的脑模拟物。