Djimeu Eric W, Brown Annette N
*International Initiative for Impact Evaluation (3ie), Washington, DC; and †Department of Research and Evaluation Strategic Initiative, FHI 360, Washington, DC.
J Acquir Immune Defic Syndr. 2016 Oct 1;72 Suppl 4(Suppl 4):S321-S325. doi: 10.1097/QAI.0000000000001161.
Seven new impact evaluations of pilot programs for increasing the demand for voluntary medical male circumcision (VMMC) provide evidence of what works and what does not. The study findings suggest that financial compensation designed to relieve the opportunity or transportation costs from undergoing the procedure can increase the uptake of VMMC. There is also evidence that programs using peer influence can be effective, although so far only sports-based programs demonstrate a strong effect. We explore the strength of evidence in each of these 7 studies to better interpret the findings for policy making.
We perform a risk of bias assessment and conduct power calculations using actual values for each of the 7 studies.
Three of the 7 studies have a medium risk of bias, whereas the other 4 have a low risk of bias. All but 2 of the studies have adequate power to detect meaningful effects. In the 2 with insufficient power, the estimated effects are large but statistically insignificant.
The positive evidence that financial incentives presented as compensation for opportunity costs to men seeking and obtaining VMMC can increase uptake comes from strong studies, which have high power and low to medium risk of bias. The positive evidence that a comprehensive sports-based program for young men can increase uptake also comes from a strong study. The strength of the studies further validates these findings.
七项关于增加男性自愿医学包皮环切术(VMMC)需求的试点项目的新影响评估提供了有效和无效措施的证据。研究结果表明,旨在减轻接受该手术的机会成本或交通成本的经济补偿可以提高VMMC的接受率。也有证据表明,利用同伴影响的项目可能有效,尽管到目前为止只有基于体育的项目显示出强大的效果。我们探讨这7项研究中每项研究的证据强度,以便更好地解释研究结果以供决策参考。
我们进行偏倚风险评估,并使用这7项研究各自的实际值进行功效计算。
7项研究中有3项存在中度偏倚风险,而其他4项存在低度偏倚风险。除2项研究外,所有研究都有足够的功效来检测有意义的效果。在2项功效不足的研究中,估计的效果很大,但在统计学上不显著。
关于向寻求并接受VMMC的男性提供机会成本补偿的经济激励措施能够提高接受率的积极证据来自强有力的研究,这些研究具有高功效以及低至中度偏倚风险。关于一项针对年轻男性的综合性体育项目能够提高接受率的积极证据也来自一项强有力的研究。这些研究的强度进一步证实了这些发现。