Hauck Katharina D, Wang Shaolin, Vincent Charles, Smith Peter C
*Department of Infectious Disease Epidemiology, School of Public Health, Faculty of Medicine, Imperial College London, London †Department of Experimental Psychology, Medical Sciences Division, University of Oxford, Oxford ‡Imperial College Business School, Imperial College London, London, UK.
Med Care. 2017 Feb;55(2):125-130. doi: 10.1097/MLR.0000000000000631.
There is little satisfactory evidence on the harm of safety incidents to patients, in terms of lost potential health and life-years.
To estimate the healthy life-years (HLYs) lost due to 6 incidents in English hospitals between the years 2005/2006 and 2009/2010, to compare burden across incidents, and estimate excess bed-days.
The study used cross-sectional analysis of the medical records of all inpatients treated in 273 English hospitals. Patients with 6 types of preventable incidents were identified. Total attributable loss of HLYs was estimated through propensity score matching by considering the hypothetical remaining length and quality of life had the incident not occurred.
The 6 incidents resulted in an annual loss of 68 HLYs and 934 excess bed-days per 100,000 population. Preventable pressure ulcers caused the loss of 26 HLYs and 555 excess bed-days annually. Deaths in low-mortality procedures resulted in 25 lost life-years and 42 bed-days. Deep-vein thrombosis/pulmonary embolisms cost 12 HLYs, and 240 bed-days. Postoperative sepsis, hip fractures, and central-line infections cost <6 HLYs and 100 bed-days each.
The burden caused by the 6 incidents is roughly comparable with the UK burden of Multiple Sclerosis (80 DALYs per 100,000), HIV/AIDS and Tuberculosis (63 DALYs), and Cervical Cancer (58 DALYs). There were marked differences in the harm caused by the incidents, despite the public attention all of them receive. Decision makers can use the results to prioritize resources into further research and effective interventions.
就潜在健康和生命年损失而言,关于安全事件对患者造成伤害的令人满意的证据很少。
估计2005/2006年至2009/2010年间英国医院6起事件导致的健康生命年(HLYs)损失,比较各事件的负担,并估计额外的住院天数。
该研究对273家英国医院所有住院患者的病历进行横断面分析。识别出发生6种可预防事件的患者。通过倾向得分匹配估计HLYs的总归因损失,同时考虑假设事件未发生时的剩余寿命长度和生活质量。
这6起事件导致每10万人每年损失68个HLYs和934个额外住院天数。可预防的压疮每年导致26个HLYs损失和555个额外住院天数。低死亡率手术中的死亡导致25个生命年损失和42个住院天数。深静脉血栓形成/肺栓塞造成12个HLYs损失和240个住院天数。术后脓毒症、髋部骨折和中心静脉感染分别造成<6个HLYs损失和100个住院天数。
这6起事件造成的负担大致相当于英国多发性硬化症(每10万人80个伤残调整生命年)、艾滋病毒/艾滋病和结核病(63个伤残调整生命年)以及宫颈癌(58个伤残调整生命年)的负担。尽管所有这些事件都受到公众关注,但它们造成的伤害存在显著差异。决策者可以利用这些结果将资源优先用于进一步研究和有效干预措施。