在钛上对电活性功能膜进行极化以诱导成骨分化。
Polarization of an electroactive functional film on titanium for inducing osteogenic differentiation.
作者信息
Zhou Zhengnan, Li Weiping, He Tianrui, Qian Lei, Tan Guoxin, Ning Chengyun
机构信息
School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China.
Guangdong Key Laboratory of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou 510006, China.
出版信息
Sci Rep. 2016 Oct 20;6:35512. doi: 10.1038/srep35512.
To enhance the surface bioactivity of titanium (Ti) prostheses, an electroactive polyvinylidene fluoride (PVDF) film was prepared on a Ti substrate to provide a mimetic of the electrical microenvironment, which facilitated the performance of cell functions. The results of cell proliferation and differentiation assays indicated that polarization of the PVDF-Ti (PTi) altered its surface charge, thus inducing adhesion, proliferation and osteogenic differentiation of cells. The polarized PVDF-Ti (PPTi) may therefore find applications in bone regeneration.
为提高钛（Ti）假体的表面生物活性，在Ti基底上制备了一种电活性聚偏二氟乙烯（PVDF）薄膜，以模拟电微环境，促进细胞功能的发挥。细胞增殖和分化测定结果表明，PVDF-Ti（PTi）的极化改变了其表面电荷，从而诱导细胞的粘附、增殖和成骨分化。因此，极化的PVDF-Ti（PPTi）可能在骨再生中得到应用。
Zotero 插件