Baek Seung-Soo
Department of Sport & Health Science, College of Natural Science, Sangmyung University, Seoul, Korea.
J Exerc Rehabil. 2016 Oct 31;12(5):380-385. doi: 10.12965/jer.1632808.404. eCollection 2016 Oct.
The functions of adult hippocampal neurogenesis have been extensively investigated during the past decade. Numerous studies have shown that adult neurogenesis may play an important role in the hippocampal-dependent learning and memory. This study evaluated the influence of exercise on hippocampal neurogenesis, neural plasticity, neurotrophic factors, and cognition. Areas of research focused on enhancing effect of exercise for adult hippocampal neurogenesis and protective role of exercise against brain diseases. The present study suggests that exercise improves brain functions and prevents decline of cognition across the lifespan. Understanding of neurobiological mechanisms of exercise on brain functions may lead to the development of novel therapeutic strategy for neurodegenerative disorders.
在过去十年中,成年海马体神经发生的功能得到了广泛研究。大量研究表明,成年神经发生可能在海马体依赖的学习和记忆中发挥重要作用。本研究评估了运动对海马体神经发生、神经可塑性、神经营养因子和认知的影响。研究领域集中在运动对成年海马体神经发生的增强作用以及运动对脑部疾病的保护作用。本研究表明,运动可改善脑功能并预防认知能力在整个生命周期中的衰退。对运动影响脑功能的神经生物学机制的理解可能会导致开发出针对神经退行性疾病的新型治疗策略。