复杂DNA砖组装

Complex DNA Brick Assembly.

作者信息

Ong Luvena L, Ke Yonggang

机构信息

Wyss Institute for Biologically Inspired Engineering, Harvard University, CLSB 5th Floor, Blackfan Circle, Boston, MA, 02115, USA.

The Harvard-MIT Health Sciences and Technology Program, MIT, Cambridge, MA, 02139, USA.

出版信息

Methods Mol Biol. 2017;1500:41-49. doi: 10.1007/978-1-4939-6454-3_4.

DOI:10.1007/978-1-4939-6454-3_4

PMID:27813000

Abstract

DNA nanostructures are a useful technology for precisely organizing and manipulating nanomaterials. The DNA bricks method is a modular and versatile platform for applications requiring discrete or periodic structures with complex three-dimensional features. Here, we describe how structures are designed from the fundamental strand architecture through assembly and characterization of the formed structures.

摘要

DNA纳米结构是一种用于精确组织和操纵纳米材料的有用技术。DNA砖块方法是一个模块化且通用的平台，适用于需要具有复杂三维特征的离散或周期性结构的应用。在这里，我们描述了如何从基本链结构出发，通过所形成结构的组装和表征来设计结构。