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英格兰和威尔士创伤性心脏骤停的流行病学与病因学——一项回顾性数据库分析

Epidemiology and aetiology of traumatic cardiac arrest in England and Wales - A retrospective database analysis.

作者信息

Barnard Ed, Yates David, Edwards Antoinette, Fragoso-Iñiguez Marisol, Jenks Tom, Smith Jason E

机构信息

Institute of Naval Medicine, Crescent Road, Alverstoke, UK; Academic Department of Military Emergency Medicine, Royal Centre for Defence Medicine (Research & Academia), Birmingham, UK.

Trauma Audit and Research Network, University of Manchester, Salford Royal NHS Foundation Trust, Manchester, UK.

出版信息

Resuscitation. 2017 Jan;110:90-94. doi: 10.1016/j.resuscitation.2016.11.001. Epub 2016 Nov 14.

Abstract

BACKGROUND

Historically, reported survival from traumatic cardiac arrest (TCA) was extremely low. More recent publications have recorded survival to discharge of up to 8%. This improvement is likely to be multi-factorial; however, there are currently no published data describing the epidemiology or aetiology of TCA in England and Wales to guide future practice improvement.

METHODS

Population-based analysis of 2009-2015 Trauma Audit and Research Network (TARN) data. The primary aim was to describe the 30-day survival following TCA. Patients of all ages with traumatic cardiac arrest pre-hospital or in the emergency department (ED) were included. Data are described as number (%), and median [interquartile range]. Two-group analysis with Chi-squared test was performed.

RESULTS

During the study period 227,944 patients were included in the TARN database. Seven hundred and five (0.3%) suffered TCA: 74.3% were male, aged 44.3 [25.2-83.2] years, ISS 29 [21-75], and 601 (85.2%) had blunt injuries. 612 (86.8%) had a severe traumatic brain injury and or severe haemorrhage. Overall 30-day survival was 7.5% (95%CI 5.6-9.5) - 'pre-hospital only' TCA 11.5%, 'ED only' TCA 3.9%, p<0.02. No patients who were in TCA both pre-hospital and in the ED survived.

CONCLUSION

This study has shown that short-term survival from TCA in this large civilian registry is 7.5%. Early and aggressive management of patients with TCA, using protocols that target the reversible causes of TCA, should be initiated. Further work to establish novel ways to manage patients with reversible causes of TCA is indicated. Resuscitation in this patient group is not futile.

摘要

背景

历史上,创伤性心脏骤停(TCA)后的报告生存率极低。最近的出版物记录了高达8%的出院生存率。这种改善可能是多因素的;然而,目前尚无关于英格兰和威尔士TCA的流行病学或病因学的公开数据来指导未来实践的改进。

方法

基于人群对2009 - 2015年创伤审计与研究网络(TARN)数据进行分析。主要目的是描述TCA后的30天生存率。纳入所有年龄在院前或急诊科(ED)发生创伤性心脏骤停的患者。数据以数量(%)和中位数[四分位间距]表示。采用卡方检验进行两组分析。

结果

在研究期间,TARN数据库纳入了227,944例患者。705例(0.3%)发生了TCA:74.3%为男性,年龄44.3[25.2 - 83.2]岁,损伤严重程度评分(ISS)为29[21 - 75],601例(85.2%)为钝性损伤。612例(86.8%)有严重创伤性脑损伤和/或严重出血。总体30天生存率为7.5%(95%置信区间5.6 - 9.5)——“仅院前”TCA为11.5%,“仅急诊科”TCA为3.9%,p<0.02。院前和急诊科均发生TCA的患者无一人存活。

结论

本研究表明,在这个大型平民登记系统中,TCA的短期生存率为7.5%。应启动针对TCA可逆病因的方案,对TCA患者进行早期积极管理。需要开展进一步工作以建立管理TCA可逆病因患者的新方法。对该患者群体进行复苏并非徒劳。

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