肝脏移植器官温度的持续监测：灌注液细菌污染与早期预后的关系。
Continuous monitoring of the liver graft temperature: relationship between bacterial contamination of the perfusion fluid and early outcome.
作者信息
Levi Sandri Giovanni Battista, Meniconi Roberto Luca, Colasanti Marco, Guglielmo Nicola, de Werra Edoardo, Mascianà Gianluca, Tortorelli Giovanni, Ferraro Daniele, Burocchi Mirco, Campanelli Alessandra, Scotti Andrea, Visco-Comandini Ubaldo, Santoro Roberto, Lepiane Pasquale, Vennarecci Giovanni, Ettorre Giuseppe Maria
机构信息
Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Italy.
Department of Clinical, "Lazzaro Spallanzani" National Institute for Infectious Diseases, Rome, Italy.
出版信息
Ann Transl Med. 2016 Oct;4(20):397. doi: 10.21037/atm.2016.10.46.
BACKGROUND
A potential mechanism of the infection would be an infected donor, contamination at the time of the infusion and/or packaging, back-table procedure, and finally during the transplantation, all are potential sources of infection. The aim of our study is to analyze the incidence and significance of infection in the preservation solution according with the graft temperature. The second aim was to analyze the impact graft temperature on the clinical infections and the ischemia reperfusion injury.
METHODS
Sixteen donors were prospectively included in this study, including 9 males and 7 females. The liver graft temperature monitoring shows variation in four different phases: at the harvesting beginning, before the graft packaging, at the beginning of the backtable, at the end of the backtable.
RESULTS
There was no correlation between the functionality of the graft and the temperature of the perfusion fluid.
CONCLUSIONS
In conclusion, we did not found a correlation between graft temperature, culture of the preservation solution and early post-transplant follow up.
背景
感染的一个潜在机制可能是供体受感染、输注和/或包装时受到污染、后台操作过程以及最终在移植过程中，所有这些都是潜在的感染源。我们研究的目的是根据移植物温度分析保存液中感染的发生率和意义。第二个目的是分析移植物温度对临床感染和缺血再灌注损伤的影响。
方法
本研究前瞻性纳入了16名供体，其中男性9名，女性7名。肝移植物温度监测显示在四个不同阶段存在变化：在开始获取时、移植物包装前、后台操作开始时、后台操作结束时。
结果
移植物功能与灌注液温度之间无相关性。
结论
总之，我们未发现移植物温度、保存液培养结果与移植后早期随访之间存在相关性。
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