Lisianyĭ N I, Markova O V, Prikhodchenko I A, Primushko L I
Zh Vopr Neirokhir Im N N Burdenko. 1989 Mar-Apr(2):33-5.
The authors compared the values of the immune status of patients with glial brain tumor of grade III-IV anaplasia in the left and right side in the preoperative period. In patients with the tumor in the right hemisphere, in the frontotemporal region in particular, the absolute number of rosette-forming cells in peripheral blood and the blast-transformation activity of lymphocytes in response to phytohemagglutinin were reduced significantly (p less than 0.05) as compared to the values in patients with the tumor on the left side. The number of B-lymphocytes and the blood immunoglobulin level were not changed. The possible mechanisms of the revealed differences are discussed with due account of data on immunogenesis regulation by the left hemisphere.
作者比较了术前III-IV级间变性胶质脑肿瘤患者左侧和右侧免疫状态的值。在右半球尤其是额颞区有肿瘤的患者中,与左侧有肿瘤的患者相比,外周血中玫瑰形成细胞的绝对数量以及淋巴细胞对植物血凝素反应的母细胞转化活性显著降低(p小于0.05)。B淋巴细胞数量和血液免疫球蛋白水平未发生变化。结合左半球免疫发生调节的数据,对所揭示差异的可能机制进行了讨论。