Hirano Taizou, Miyauchi Eisaku, Inoue Akira, Igusa Ryotaro, Chiba Shigeki, Sakamoto Kazuhiro, Sugiura Hisatoshi, Kikuchi Toshiaki, Ichinose Masakazu
Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan.
Department of Palliative Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan.
Respir Investig. 2016 Nov;54(6):494-499. doi: 10.1016/j.resinv.2016.04.006. Epub 2016 Jul 15.
Pseudo-achalasia with lung cancer is a rare complication. We present 2 cases of pseudo-achalasia with lung cancer and summarize previous reports. The previous reports suggested that lung cancer can be complicated with pseudo-achalasia caused by paraneoplastic neurological syndromes rather than direct invasion of the tumor cells to the lower esophageal sphincter, irrespective of the histology of the lung cancer; this can strongly influence the performance status. Treatment for pseudo-achalasia improves not only the symptoms, but also the performance status. Therefore, pseudo-achalasia should be considered when lung cancer patients present with dysphagia without other known causes.
肺癌合并假性贲门失弛缓症是一种罕见的并发症。我们报告2例肺癌合并假性贲门失弛缓症的病例,并总结既往报道。既往报道提示,无论肺癌的组织学类型如何,肺癌可合并由副肿瘤性神经综合征引起的假性贲门失弛缓症,而非肿瘤细胞直接侵犯食管下括约肌;这会对患者的体能状态产生重大影响。假性贲门失弛缓症的治疗不仅能改善症状,还能改善体能状态。因此,当肺癌患者出现无其他已知病因的吞咽困难时,应考虑假性贲门失弛缓症的可能。