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接受腹腔镜子宫固定术的女性的临床结局:一项系统评价。

Clinical outcomes in women undergoing laparoscopic hysteropexy: A systematic review.

作者信息

Nair R, Nikolopoulos K I, Claydon L S

机构信息

Department of Obstetrics and Gynaecology, Queen's Hospital, Rom Valley Way, Romford, Essex, UK.

Department of Obstetrics and Gynaecology, Queen's Hospital, Rom Valley Way, Romford, Essex, UK.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2017 Jan;208:71-80. doi: 10.1016/j.ejogrb.2016.11.019. Epub 2016 Nov 20.

Abstract

OBJECTIVES

To systematically review the current evidence on the anatomic and functional outcomes in women undergoing laparoscopic hysteropexy.

STUDY DESIGN

An electronic database search was undertaken (2000-2016). Keywords were: "laparoscopy", "hysteropexy", "cervicopexy", "uterine suspension", "uterosacral plication". References of identified studies as well as abstracts from conferences were considered. We restricted the search to humans, female patients and currently used surgical procedures. Studies with ≥5 cases in English language and published in 2000 or later, were included. After the initial yield, studies were selected following title screening, abstract and full text scrutiny.

RESULTS

A total of 17 studies were deemed suitable for inclusion in the review. A total of 770 patients in 17 studies received the intervention being studied (laparoscopic hysteropexy) and were assessed post-operatively with pooled success rates of 85.32% (95%CI: ±2.5). Laparoscopic suture hysteropexy has pooled success of 70.5% (95%CI:±5.33) whereas the pooled success of the suspension to the sacral promontory using mesh or tape is 92% (95%CI: ±2.53). One small study on suspension to the anterior abdominal wall (28 cases) and one to the pectineal ligament (18 cases) have shown 96.4% (95%CI:±6.9) and 94.5% (95%CI:±10.53) objective success rates respectively.

CONCLUSION

Laparoscopic hysteropexy was associated with good anatomic cure rates of greater than 90% in majority of the studies. There was an improvement in symptoms, and good subjective cure rates in 73%-100% of the patients. Reoperation rates were low in most studies ranging from around 0%-28%. Complications rates were generally low. Laparoscopic hysteropexy is a feasible alternative for women needing surgical correction of uterovaginal prolapse and who desire conservation of the uterus.

摘要

目的

系统评价接受腹腔镜子宫固定术的女性患者的解剖学和功能学结局的现有证据。

研究设计

进行电子数据库检索(2000 - 2016年)。关键词为:“腹腔镜检查”、“子宫固定术”、“宫颈固定术”、“子宫悬吊术”、“子宫骶骨襞成形术”。纳入已识别研究的参考文献以及会议摘要。检索限于人类、女性患者和当前使用的手术方法。纳入2000年或之后发表的、英文撰写且病例数≥5例的研究。在初步筛选后,通过标题筛选、摘要和全文审查来选择研究。

结果

共有17项研究被认为适合纳入本综述。17项研究中的770例患者接受了所研究的干预措施(腹腔镜子宫固定术),术后评估的总体成功率为85.32%(95%置信区间:±2.5)。腹腔镜缝合子宫固定术的总体成功率为70.5%(95%置信区间:±5.33),而使用网片或吊带悬吊至骶岬的总体成功率为92%(95%置信区间:±2.53)。一项关于悬吊至前腹壁的小型研究(28例)和一项关于悬吊至耻骨梳韧带的小型研究(18例)分别显示客观成功率为96.4%(95%置信区间:±6.9)和94.5%(95%置信区间:±10.53)。

结论

在大多数研究中,腹腔镜子宫固定术的解剖学治愈率高于90%。症状有所改善,73% - 100%的患者主观治愈率良好。大多数研究中的再次手术率较低,范围约为0% - 28%。并发症发生率总体较低。对于需要手术矫正子宫阴道脱垂且希望保留子宫的女性,腹腔镜子宫固定术是一种可行的替代方法。

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