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2型糖尿病患者中Rho激酶活性增加的数据。

Data for increased Rho kinase activity in type 2 diabetic patients.

作者信息

Liu Lei, Tan Lun, Lai Jinsheng, Li Sheng, Wang Dao Wen

机构信息

Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Data Brief. 2016 Nov 16;9:978-982. doi: 10.1016/j.dib.2016.11.032. eCollection 2016 Dec.

Abstract

The data presented in this article are related to the research article entitled "Enhanced Rho-Kinase Activity: Pathophysiological Relevance in Type 2 Diabetes" [1]. Rho-Kinase has attracted a great deal of interest as a novel therapeutic target in cardiovascular diseases. These data describe the observed relationship of Rho-Kinase activity with type 2 diabetic patients. Rho-Kinase activity is determined by immunoblotting of peripheral blood leukocytes with the Phospho-Thr853 in the myosin-binding subunit of myosin light-chain phosphatase. The level of IL-6 is measured using .

摘要

本文所呈现的数据与题为《增强的Rho激酶活性:2型糖尿病中的病理生理相关性》[1]的研究文章相关。作为心血管疾病中的一个新型治疗靶点,Rho激酶已引起了广泛关注。这些数据描述了观察到的Rho激酶活性与2型糖尿病患者之间的关系。Rho激酶活性通过用肌球蛋白轻链磷酸酶的肌球蛋白结合亚基中的磷酸化苏氨酸853对外周血白细胞进行免疫印迹来确定。白细胞介素-6的水平使用……进行测量。 (注:原文中“using”后内容缺失)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0685/5120266/e8effa8c7b73/gr1.jpg

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