在患有前交叉韧带损伤的年轻成年人中，肌肉功能与未来患者报告的结果相关。
Muscle function is associated with future patient-reported outcomes in young adults with ACL injury.
作者信息
Flosadottir Vala, Roos Ewa M, Ageberg Eva
机构信息
Department of Health Sciences , Lund University , Lund , Sweden.
Research Unit for Musculoskeletal Function and Physiotherapy, Institute of Sports and Clinical Biomechanics, University of Southern Denmark , Odense , Denmark.
出版信息
BMJ Open Sport Exerc Med. 2016 Oct 10;2(1):e000154. doi: 10.1136/bmjsem-2016-000154. eCollection 2016.
BACKGROUND/AIM: Consequences of an anterior cruciate ligament (ACL) injury include worse patient-reported outcomes (PROs) and a decrease in activity level. Muscle function can be improved by targeted exercise. Our aims were to investigate cross-sectional and longitudinal associations among lower extremity muscle function and PROs after ACL injury.
METHODS
Fifty-four participants (15 women, mean 30 years) with ACL injury or reconstruction, from the Knee Anterior Cruciate Ligament, Nonsurgical versus Surgical Treatment (KANON) trial (ISRCTN84752559), were assessed with hop performance, muscle power and postural orientation 3 years (SD 0.85) after ACL injury. PROs at 3 and 5 years after injury included Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales Function in sport and recreation (KOOS Sport/rec) and Knee-related Quality of life (KOOS QoL), KOOS item Q3 (KOOS Q3), Tegner Activity Scale and Activity Rating Scale (ARS). Partial Spearman's rank-order correlation was used to analyse correlations between muscle function and PROs, controlling for gender and treatment.
RESULTS
Numerous cross-sectional correlations were observed between muscle function and PROs (r≈0.3-0.5, p≤0.045). Worse hop performance and worse postural orientation were associated with worse KOOS scores 2 years later (r≥0.280, p≤0.045). Worse muscle power was associated with lower future ARS scores (r=0.281, p=0.044).
CONCLUSIONS
The moderate associations suggest that improving muscle function during rehabilitation could improve present and future PROs.
背景/目的：前交叉韧带（ACL）损伤的后果包括患者报告的结果（PROs）较差以及活动水平下降。针对性锻炼可改善肌肉功能。我们的目的是研究ACL损伤后下肢肌肉功能与PROs之间的横断面和纵向关联。
方法
来自膝关节前交叉韧带非手术与手术治疗（KANON）试验（ISRCTN84752559）的54名ACL损伤或重建患者（15名女性，平均年龄30岁）在ACL损伤3年（标准差0.85）后接受了单腿跳性能、肌肉力量和姿势定向评估。损伤后3年和5年的PROs包括膝关节损伤和骨关节炎结局评分（KOOS）子量表运动和娱乐功能（KOOS Sport/rec）、膝关节相关生活质量（KOOS QoL）、KOOS项目Q3（KOOS Q3）、特格纳活动量表和活动评级量表（ARS）。采用偏斯皮尔曼等级相关分析肌肉功能与PROs之间的相关性，并对性别和治疗进行控制。
结果
观察到肌肉功能与PROs之间存在许多横断面相关性（r≈0.3 - 0.5，p≤0.045）。较差的单腿跳性能和姿势定向与2年后较差的KOOS评分相关（r≥0.280，p≤0.045）。较差的肌肉力量与未来较低的ARS评分相关（r = 0.281，p = 0.044）。
结论
中等程度的关联表明，在康复过程中改善肌肉功能可能会改善当前和未来的PROs。
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