Geng J, Chen X L, Wang X D, Guo X Y, Li M
Department of Anesthesiology, Peking University Third Hospital, Beijing 100191, China.
Zhonghua Yi Xue Za Zhi. 2016 Nov 22;96(43):3459-3463. doi: 10.3760/cma.j.issn.0376-2491.2016.43.004.
To verify whether preprocedural ultrasound of the lumbar spine could improve first-attempt success rate (defined as a successful neuraxial anesthesia with only one skin puncture) of neuraxial block in elderly patients. From septemble 2015 to February 2016, 200 elderly patients undergoing lower-limb surgery with neuraxial block at the Peking Universty Third Hospital were enrolled in this study.RandA 1.0 software was used to randomize patients into two groups: conventional surface landmark-guided group (group LM) and ultrasound-assisted group (group US). Ultrasound scanning of the lumbar spine was performed to determine the suitable insertion point of US group, using a low-frequency (2-5 MHz) curved-array probe in both paramedian sagittal oblique plane and transverse median plane.Spinal anesthesia was done via the paramedian approach.The primary outcome was the rate of successful access to subarchnoid space on the first needle insertion attempt.Secondary outcomes included the following: number of needle insertion attempts, number of needle redirection times, actual epidural needle insertion depth, time taken to eastablish landmarks, time taken to perform the spinal anesthesia (the duration between local infiltration and bupivacaine injection), procedure time (the duration from sterilizing the back to converting into supine position), total time (the sum of the time to establish landmarks and the procedure time), adverse events during the procedure and anesthesia related complications. A total of 191 patients successfully received combined spinal-epidural anesthesia by resident anesthesiologists, 9 patients (7 patients in group LM vs 2 patients in group US) failed.The first-attempt success rate in group LM was 37.6%, while the first-attempt success rate in group US was 68.4%, the difference between the two groups was significant (χ=18.112, <0.01). In group LM, the number of needle insertion attempts and needle redirection attempts were 2(1, 3) and 5(3, 10), respectively. In group US, the number of needle insertion attempts and needle redirection attempts were 1(1, 2) and 3(0, 5), respectively.The differences in the number of needle insertion attempts and needle redirection attempts between the two groups were significant (=-4.132, -4.077, all <0.01). In group US, the time spent on determining the insertion point, on puncture, on finishing the procedure and the total time were as the following: 2.8(2.6, 3.1), 2.5(1.8, 4.1), 7.8(6.5, 8.9), 10.6(9.5, 11.9) min.In contrast, in group LM, those indices were as the following: 0.4(0.3, 0.4), 4.1(2.2, 6.3), 8.8(7.5, 11.4), 9.2(7.8, 11.9) min.There were significant differences in the above factors between the two groups (=-11.931, -4.025, -3.550, -3.290, all <0.01). The paramedian sagittal oblique scanning image was superior to that of the transverse median plane. For elderly patients, ultrasound imaging before neuraxial block increases first-attempt success rate, decreases puncture time.The strengths of prepuncture ultrasound scanning outweighs its longer total time.
为验证腰椎术前超声检查能否提高老年患者神经轴阻滞首次穿刺成功率(定义为仅一次皮肤穿刺即成功实施神经轴麻醉)。2015年9月至2016年2月,北京大学第三医院200例行下肢手术并接受神经轴阻滞的老年患者纳入本研究。使用RandA 1.0软件将患者随机分为两组:传统体表标志引导组(LM组)和超声辅助组(US组)。对腰椎进行超声扫描以确定US组合适的穿刺点,在旁正中矢状斜平面和横断正中平面使用低频(2 - 5 MHz)凸阵探头。经旁正中入路实施脊髓麻醉。主要结局为首次进针尝试时成功进入蛛网膜下腔的比率。次要结局包括以下内容:进针尝试次数、针调整方向次数、实际硬膜外针穿刺深度、确定体表标志所需时间、实施脊髓麻醉所需时间(局部浸润至布比卡因注射的时长)、操作时间(从背部消毒至转为仰卧位的时长)总时间(确定体表标志时间与操作时间之和)、操作过程中的不良事件及麻醉相关并发症。共有191例患者由住院麻醉医师成功实施腰麻 - 硬膜外联合麻醉,9例患者失败(LM组7例,US组2例)。LM组首次穿刺成功率为37.6%,而US组首次穿刺成功率为68.4%,两组差异有统计学意义(χ = 18.112,P < 0.01)。LM组进针尝试次数和针调整方向次数分别为2(1,3)次和5(3,10)次。US组进针尝试次数和针调整方向次数分别为1(1,2)次和3(0,5)次。两组进针尝试次数和针调整方向次数差异有统计学意义(P = -4.132,P = -4.077,均P < 0.01)。US组确定穿刺点、穿刺、完成操作及总时间分别为:2.8(2.6,3.1)分钟、2.5(1.8,4.1)分钟、7.8(6.5,8.9)分钟、10.6(9.5,11.9)分钟。相比之下,LM组上述指标分别为:0.4(0.3,0.4)分钟、4.1(2.2,6.3)分钟、8.8(7.5,11.4)分钟、9.2(7.8,11.9)分钟。两组上述因素差异有统计学意义(P = -1,1.931,P = -4.025,P = -3.550,P = -3.290,均P < 0.01)。旁正中矢状斜扫描图像优于横断正中平面图像。对于老年患者,神经轴阻滞前超声成像可提高首次穿刺成功率,缩短穿刺时间。穿刺前超声扫描的优势超过其总时间较长的劣势。