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[因巨天冬氨酸氨基转移酶(AST)的存在导致天冬氨酸氨基转移酶(AST)持续升高:一例报告]

[Persistent elevation of aspartate aminotransferase (AST) due to the presence of macro-AST: Report of one case].

作者信息

Bustamante Verónica, Arab Juan Pablo, Terc Florencia, Poggi Helena, Goycoolea Manuela, Arrese Marco, Quiroga Teresita, Benítez Carlos

出版信息

Rev Med Chil. 2016 Aug;144(8):1078-1082. doi: 10.4067/S0034-98872016000800017.

DOI:10.4067/S0034-98872016000800017
PMID:27905656
Abstract

We report an asymptomatic 23-year-old woman with an isolated and persistent increase in serum levels of aspartate aminotransferase (AST). An extensive work up including laboratory and image testing revealed no abnormalities thus suggesting the presence of macro-AST. A polyethylene glycol (PEG) precipitation assay was performed and confirmed the presence of macro-AST.

摘要

我们报告了一名23岁无症状女性,其血清天冬氨酸转氨酶(AST)水平单独且持续升高。包括实验室和影像检查在内的全面检查未发现异常,因此提示存在巨AST。进行了聚乙二醇(PEG)沉淀试验,证实了巨AST的存在。

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引用本文的文献

1
Macro-aspartate aminotransferase in a healthy woman.一名健康女性体内的巨天冬氨酸转氨酶
Clin Mol Hepatol. 2020 Jul;26(3):378-381. doi: 10.3350/cmh.2020.0069. Epub 2020 Jun 23.
2
Isolated elevation of aspartate aminotransferase (AST) in an asymptomatic patient due to macro-AST.无症状患者因巨天冬氨酸氨基转移酶(AST)导致AST单独升高。
J Clin Lab Anal. 2019 Feb;33(2):e22690. doi: 10.1002/jcla.22690. Epub 2018 Oct 15.
3
Distribution of serum concentrations reported for macroenzyme aspartate aminotransferase (macro-AST).报道的血清中巨酶天冬氨酸氨基转移酶(巨AST)浓度的分布情况。
Pract Lab Med. 2017 May 17;8:65-69. doi: 10.1016/j.plabm.2017.05.003. eCollection 2017 Aug.