Parand Anam, Garfield Sara, Vincent Charles, Franklin Bryony Dean
Department of Social Psychology, The London School of Economics, London, United Kingdom / The National Institute for Health Research (NIHR) Imperial Patient Safety Translational Research Centre, Imperial College London, London, United Kingdom.
Centre for Medication Safety and Service Quality, Imperial College Healthcare NHS Trust / Research Department of Practice and Policy, UCL School of Pharmacy, London, United Kingdom.
PLoS One. 2016 Dec 1;11(12):e0167204. doi: 10.1371/journal.pone.0167204. eCollection 2016.
Medications are mostly taken in patients' own homes, increasingly administered by carers, yet studies of medication safety have been largely conducted in the hospital setting. We aimed to review studies of how carers cause and/or prevent medication administration errors (MAEs) within the patient's home; to identify types, prevalence and causes of these MAEs and any interventions to prevent them.
A narrative systematic review of literature published between 1 Jan 1946 and 23 Sep 2013 was carried out across the databases EMBASE, MEDLINE, PSYCHINFO, COCHRANE and CINAHL. Empirical studies were included where carers were responsible for preventing/causing MAEs in the home and standardised tools used for data extraction and quality assessment.
Thirty-six papers met the criteria for narrative review, 33 of which included parents caring for children, two predominantly comprised adult children and spouses caring for older parents/partners, and one focused on paid carers mostly looking after older adults. The carer administration error rate ranged from 1.9 to 33% of medications administered and from 12 to 92.7% of carers administering medication. These included dosage errors, omitted administration, wrong medication and wrong time or route of administration. Contributory factors included individual carer factors (e.g. carer age), environmental factors (e.g. storage), medication factors (e.g. number of medicines), prescription communication factors (e.g. comprehensibility of instructions), psychosocial factors (e.g. carer-to-carer communication), and care-recipient factors (e.g. recipient age). The few interventions effective in preventing MAEs involved carer training and tailored equipment.
This review shows that home medication administration errors made by carers are a potentially serious patient safety issue. Carers made similar errors to those made by professionals in other contexts and a wide variety of contributory factors were identified. The home care setting should be a priority for the development of patient safety interventions.
药物大多是在患者自己家中服用,越来越多地由护理人员给药,但药物安全性研究大多是在医院环境中进行的。我们旨在回顾关于护理人员如何在患者家中导致和/或预防用药错误(MAE)的研究;确定这些用药错误的类型、发生率和原因以及任何预防措施。
对1946年1月1日至2013年9月23日期间发表在EMBASE、MEDLINE、PSYCHINFO、COCHRANE和CINAHL数据库中的文献进行叙述性系统综述。纳入了护理人员负责在家庭中预防/导致用药错误且使用标准化工具进行数据提取和质量评估的实证研究。
36篇论文符合叙述性综述的标准,其中33篇涉及照顾儿童的父母,2篇主要是成年子女和配偶照顾老年父母/伴侣,1篇关注主要照顾老年人的付费护理人员。护理人员给药错误率在给药的1.9%至33%之间,给药的护理人员中有12%至92.7%出现错误。这些错误包括剂量错误、漏服、用药错误以及给药时间或途径错误。促成因素包括护理人员个体因素(如护理人员年龄)、环境因素(如储存)、药物因素(如药物数量)、处方沟通因素(如说明书的易懂性)、心理社会因素(如护理人员之间的沟通)以及受照顾者因素(如受照顾者年龄)。少数有效预防用药错误的干预措施包括护理人员培训和定制设备。
本综述表明,护理人员在家中给药错误是一个潜在的严重患者安全问题。护理人员出现的错误与其他情况下专业人员出现的错误类似,并且确定了多种促成因素。家庭护理环境应成为患者安全干预措施开发的重点。