Suppr超能文献

Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons.

作者信息

Ibanez Vinzon, Vaitkus Kestis, Rivers Angela, Molokie Robert, Cui Shuaiying, Engel James Douglas, DeSimone Joseph, Lavelle Donald

机构信息

Department of Medicine, University of Illinois at Chicago, Chicago, IL.

Jesse Brown Veterans Affairs Medical Center, Chicago, IL.

出版信息

Blood. 2017 Jan 12;129(2):260-263. doi: 10.1182/blood-2016-10-746727. Epub 2016 Dec 1.

Abstract
摘要

相似文献

1
Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons.
Blood. 2017 Jan 12;129(2):260-263. doi: 10.1182/blood-2016-10-746727. Epub 2016 Dec 1.
2
The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice.
Blood. 2015 Jul 16;126(3):386-96. doi: 10.1182/blood-2015-02-626259. Epub 2015 Jun 1.
3
Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons.
Exp Hematol. 2018 Nov;67:60-64.e2. doi: 10.1016/j.exphem.2018.08.003. Epub 2018 Aug 17.
4
Potential role of LSD1 inhibitors in the treatment of sickle cell disease: a review of preclinical animal model data.
Am J Physiol Regul Integr Comp Physiol. 2018 Oct 1;315(4):R840-R847. doi: 10.1152/ajpregu.00440.2017. Epub 2018 Aug 1.
6
The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis).
Haematologica. 2016 Jun;101(6):688-97. doi: 10.3324/haematol.2015.140749. Epub 2016 Feb 8.
7
Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis.
Blood. 2019 May 30;133(22):2455-2459. doi: 10.1182/blood.2018892737. Epub 2019 Apr 16.
8
Effect of the LSD1 inhibitor RN-1 on γ-globin and global gene expression during erythroid differentiation in baboons (Papio anubis).
PLoS One. 2023 Dec 22;18(12):e0289860. doi: 10.1371/journal.pone.0289860. eCollection 2023.

引用本文的文献

1
Effect of the LSD1 inhibitor RN-1 on γ-globin and global gene expression during erythroid differentiation in baboons (Papio anubis).
PLoS One. 2023 Dec 22;18(12):e0289860. doi: 10.1371/journal.pone.0289860. eCollection 2023.
2
Combinatorial targeting of epigenome-modifying enzymes with decitabine and RN-1 synergistically increases HbF.
Blood Adv. 2023 Aug 8;7(15):3891-3902. doi: 10.1182/bloodadvances.2022009558.
3
Epigenetic plasticity of erythroid progenitors.
Blood. 2021 Nov 4;138(18):1646-1648. doi: 10.1182/blood.2021013087.
4
An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.
Blood. 2021 Nov 4;138(18):1691-1704. doi: 10.1182/blood.2021011682.
5
Epigenetic regulation of hemoglobin switching in non-human primates.
Semin Hematol. 2021 Jan;58(1):10-14. doi: 10.1053/j.seminhematol.2020.12.001. Epub 2020 Dec 28.
6
Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations.
PLoS One. 2020 May 29;15(5):e0233468. doi: 10.1371/journal.pone.0233468. eCollection 2020.
7
Small molecule therapeutics to treat the β-globinopathies.
Curr Opin Hematol. 2020 May;27(3):129-140. doi: 10.1097/MOH.0000000000000579.
8
Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons.
Exp Hematol. 2018 Nov;67:60-64.e2. doi: 10.1016/j.exphem.2018.08.003. Epub 2018 Aug 17.
9
Potential role of LSD1 inhibitors in the treatment of sickle cell disease: a review of preclinical animal model data.
Am J Physiol Regul Integr Comp Physiol. 2018 Oct 1;315(4):R840-R847. doi: 10.1152/ajpregu.00440.2017. Epub 2018 Aug 1.
10
Targeting histone methyltransferase and demethylase in acute myeloid leukemia therapy.
Onco Targets Ther. 2017 Dec 28;11:131-155. doi: 10.2147/OTT.S145971. eCollection 2018.

本文引用的文献

1
The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis).
Haematologica. 2016 Jun;101(6):688-97. doi: 10.3324/haematol.2015.140749. Epub 2016 Feb 8.
3
The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice.
Blood. 2015 Jul 16;126(3):386-96. doi: 10.1182/blood-2015-02-626259. Epub 2015 Jun 1.
6
Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A.
Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6518-23. doi: 10.1073/pnas.1303976110. Epub 2013 Apr 1.
7
Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction.
Nat Med. 2013 Mar;19(3):291-4. doi: 10.1038/nm.3101. Epub 2013 Feb 17.
9
Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine.
Blood. 2012 Feb 2;119(5):1240-7. doi: 10.1182/blood-2011-08-371690. Epub 2011 Dec 7.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验