Kohl Johannes, Autry Anita E, Dulac Catherine
Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Center for Brain Science, Harvard University, Cambridge, MA, USA.
Sainsbury Wellcome Centre for Neural Circuits and Behaviour, London, UK.
Bioessays. 2017 Jan;39(1):1-11. doi: 10.1002/bies.201600159. Epub 2016 Dec 6.
Social interactions are essential for animals to reproduce, defend their territory, and raise their young. The conserved nature of social behaviors across animal species suggests that the neural pathways underlying the motivation for, and the execution of, specific social responses are also maintained. Modern tools of neuroscience have offered new opportunities for dissecting the molecular and neural mechanisms controlling specific social responses. We will review here recent insights into the neural circuits underlying a particularly fascinating and important form of social interaction, that of parental care. We will discuss how these findings open new avenues to deconstruct infant-directed behavioral control in males and females, and to help understand the neural basis of parenting in a variety of animal species, including humans. Please also see the video abstract here.
社交互动对于动物繁殖、保卫领地和养育后代至关重要。动物物种间社会行为的保守性表明,特定社会反应的动机及执行背后的神经通路也得以保留。神经科学的现代工具为剖析控制特定社会反应的分子和神经机制提供了新机会。在此,我们将回顾关于一种特别引人入胜且重要的社会互动形式——亲代抚育——背后神经回路的最新见解。我们将讨论这些发现如何开辟新途径来解构雄性和雌性针对幼崽的行为控制,并有助于理解包括人类在内的多种动物物种养育行为的神经基础。另请在此处查看视频摘要。