Fraaij Pieter L A, Wildschut Enno D, Houmes Robert J, Swaan Corien M, Hoebe Christian J, de Jonge H C C, Tolsma Paulien, de Kleer Isme, Pas Suzan D, Oude Munnink Bas B, Phan My V T, Bestebroer Theo M, Roosenhoff R Shanty, van Kampen Jeroen J A, Cotten Matthew, Beerens Nancy, Fouchier Ron A M, van den Kerkhof Johannes H, Timen Aura, Koopmans Marion P
Department of Viroscience Erasmus MC, Rotterdam, The Netherlands.
Department of Pediatrics, Subdivision Infectious diseases and Immunology, Erasmus MC - Sophia, Rotterdam, The Netherlands.
Euro Surveill. 2016 Dec 1;21(48). doi: 10.2807/1560-7917.ES.2016.21.48.30416.
In October 2016, a severe infection with swine influenza A(H1N1) virus of the Eurasian avian lineage occurred in a child with a previous history of eczema in the Netherlands, following contact to pigs. The patient's condition deteriorated rapidly and required life support through extracorporeal membrane oxygenation. After start of oseltamivir treatment and removal of mucus plugs, the patient fully recovered. Monitoring of more than 80 close unprotected contacts revealed no secondary cases.
2016年10月,荷兰一名曾患湿疹的儿童在接触猪后,感染了欧亚禽源甲型H1N1猪流感病毒,病情严重。患者病情迅速恶化,需要通过体外膜肺氧合进行生命支持。在开始使用奥司他韦治疗并清除黏液栓后,患者完全康复。对80多名未采取防护措施的密切接触者进行监测,未发现二代病例。