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呼吸性碱中毒速查

A Quick Reference on Respiratory Alkalosis.

作者信息

Johnson Rebecca A

机构信息

Department of Surgical Sciences, University of Wisconsin - Madison, 2015 Linden Drive, Madison, WI 53706, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2017 Mar;47(2):181-184. doi: 10.1016/j.cvsm.2016.10.005. Epub 2016 Dec 8.

Abstract

Respiratory alkalosis, or primary hypocapnia, occurs when alveolar ventilation exceeds that required to eliminate the carbon dioxide produced by tissues. Concurrent decreases in Paco, increases in pH, and compensatory decreases in blood HCO levels are associated with respiratory alkalosis. Respiratory alkalosis can be acute or chronic, with metabolic compensation initially consisting of cellular uptake of HCO and buffering by intracellular phosphates and proteins. Chronic respiratory alkalosis results in longer-lasting decreases in renal reabsorption of HCO; the arterial pH can approach near-normal values.

摘要

呼吸性碱中毒,即原发性低碳酸血症,当肺泡通气量超过消除组织产生的二氧化碳所需的通气量时发生。同时,动脉血二氧化碳分压(Paco₂)降低、pH值升高以及血液中碳酸氢根(HCO₃⁻)水平的代偿性降低与呼吸性碱中毒相关。呼吸性碱中毒可分为急性或慢性,代谢性代偿最初包括细胞摄取HCO₃⁻以及细胞内磷酸盐和蛋白质的缓冲作用。慢性呼吸性碱中毒会导致肾脏对HCO₃⁻的重吸收持续减少;动脉血pH值可接近正常水平。

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