Ferrara M, Bizzozero L, Fiumara E, D'Angelo V, Corona C, Colombo N
Department of Neurosurgery, Niguarda-Ca, Granda Hospital, Milan, Italy.
J Neurosurg Sci. 1989 Apr-Jun;33(2):219-23.
The Authors report the case of a 5-year-old boy medulloblastoma presenting with "primary" widespread diffusion in the subarachnoid spaces of the posterior fossa without true mass lesion. The diagnosis, suspected first on the basis of the computed tomography (CT) findings, was confirmed by cytological examination of the cerebrospinal fluid (CSF) and by surgery. The Authors analyse the peculiar clinical features (rapid and severe deterioration of general conditions, hyperacute course of the illness and fatal issue) and the morphological aspects of the tumor (CT and surgical findings). To our knowledge no case of "primary" dissemination of medulloblastoma was previously reported.
作者报告了一例5岁男孩的髓母细胞瘤病例,该肿瘤在小脑后窝蛛网膜下腔呈“原发性”广泛播散,无真正的肿块病变。最初根据计算机断层扫描(CT)结果怀疑诊断,经脑脊液(CSF)细胞学检查和手术得以确诊。作者分析了其特殊的临床特征(全身状况迅速严重恶化、疾病超急性病程及致命结局)以及肿瘤的形态学方面(CT和手术所见)。据我们所知,此前尚无髓母细胞瘤“原发性”播散的病例报道。