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1例产后诊断的胃肠道间质瘤病例。

A Case of a Gastrointestinal Stromal Tumor Diagnosed at the Postpartum Period.

作者信息

Kurt Sefa, Canda Aras Emre, Karadeniz Emre, Yavuzsen Tugba, Sagol Ozgul, Obuz Funda, Canda Mehmet Serefettin

机构信息

Dokuz Eylul University School of Medicine, Department of Obstetrics and Gynecology, Izmir, Turkey.

Dokuz Eylul University School of Medicine, Department of Surgery, Izmir, Turkey.

出版信息

Case Rep Obstet Gynecol. 2016;2016:3621802. doi: 10.1155/2016/3621802. Epub 2016 Nov 10.

Abstract

. We discuss a rare gastrointestinal stromal tumor (GIST) case detected at the 10th postpartum week and we want to pay attention to the challenges and improvements in the diagnosis, surgery, chemotherapy, and follow-up of this rare tumor accompanied with the review of the current literature. . A 32-year-old multiparous woman presented with abdominal swelling 10 weeks after her second vaginal birth. Abdominal examination revealed a mass starting from the pelvic level and extending to the right upper quadrant. Radiological examinations showed a solid, multiloculated, and hypervascular mass starting from the pelvis and extending to the transverse colon. mass with a 20 cm jejunal segment resection and a left pelvic side wall peritonectomy with omentectomy was performed. The pathologic examination revealed a high-risk GIST which originated from the jejunum and disseminated to the peritoneum. The patient has been given imatinib 400 mg/day since then. She did not reveal any progression during the 15-month follow-up postoperatively. . GIST tumors are rare and there is not sufficient information in the literature regarding its management. In this patient having high risk GIST and GIST sarcomatosis we successfully treated the patient by surgery and adjuvant imatinib chemotherapy.

摘要

我们讨论了一例在产后第10周发现的罕见胃肠道间质瘤(GIST)病例,并希望在回顾当前文献的同时,关注这种罕见肿瘤在诊断、手术、化疗及随访方面所面临的挑战与改进。一名32岁经产妇在第二次阴道分娩后10周出现腹部肿胀。腹部检查发现一个肿块,起自盆腔水平并延伸至右上腹。影像学检查显示一个实性、多房性、高血运肿块,起自盆腔并延伸至横结肠。行肿块切除,包括20cm空肠段切除及左盆腔侧壁腹膜切除术加网膜切除术。病理检查显示为起源于空肠并播散至腹膜的高危GIST。此后患者接受每天400mg伊马替尼治疗。术后15个月的随访期间未发现任何病情进展。GIST肿瘤较为罕见,文献中关于其治疗的信息不足。对于该患有高危GIST及GIST肉瘤病的患者,我们通过手术及辅助伊马替尼化疗成功地进行了治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d68c/5121446/edc010d67185/CRIOG2016-3621802.001.jpg

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