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[伊斯特拉次区域6个社区风湿热发病率及临床表现的变化(1962 - 1986年)]

[Changes in the incidence and clinical picture of rheumatic fever in 6 communities in the Istrian Subregion (1962-1986)].

作者信息

Capar M

出版信息

Lijec Vjesn. 1989 Jun-Jul;111(6-7):197-9.

PMID:2796574
Abstract

Two hundred patients up to 13 years of age who were admitted to the Department of Pediatrics, Pula, between 1962 and 1986 with acute rheumatic fever were studied. Of these patients, 21 (10.5%) were in relapse. During the first 12 years of follow-up, 177 patients were treated and during the last 13 years only 23 patients. The average hospital incidence declined from 2.7% in 1963 to 0.3% or less between 1975 and 1986. The average annual incidence of acute rheumatic fever in a group of patients aged 0 to 14 years decreased from 67/100,000 in 1963 to 5.4/100,000 children in 1986. Within the last 13 years of follow-up, no relapse was observed. From 1966, no patient with decompensation of the heart was treated; and from 1961, no mortality was observed as a consequence of acute rheumatic fever. There are a number of factors which influenced these good trends, such as advances in health protection of children, better primary and secondary antirheumatic prophylaxis and, of course, continued improving of the standards of living in this subregion. It is concluded that in spite of the declining incidence and milder course of acute rheumatic fever, the disease still remains a serious public health problem due to a possible cardiac damage.

摘要

对1962年至1986年间因急性风湿热入住普拉儿科的200名13岁以下儿童进行了研究。其中,21名(10.5%)处于复发状态。在随访的前12年中,有177名患者接受了治疗,而在最后13年中仅有23名患者接受治疗。医院平均发病率从1963年的2.7%下降到1975年至1986年间的0.3%或更低。0至14岁患者群体中急性风湿热的年平均发病率从1963年的67/100,000下降到1986年的5.4/100,000儿童。在随访的最后13年中,未观察到复发情况。自1966年起,未治疗过心脏失代偿患者;自1961年起,未观察到因急性风湿热导致的死亡病例。有许多因素影响了这些良好趋势,如儿童健康保护的进步、更好的一级和二级抗风湿预防措施,当然还有该次区域生活水平的持续提高。结论是,尽管急性风湿热的发病率下降且病程较轻,但由于可能导致心脏损害,该疾病仍然是一个严重的公共卫生问题。

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