Sarno Antonio, Mettivier Giovanni, Di Lillo Francesca, Russo Paolo
Dipartimento di Fisica 'Ettore Pancini', Università di Napoli Federico II, I-80126 Napoli, Italy. INFN Sezione di Napoli, I-80126 Napoli, Italy.
Phys Med Biol. 2017 Jan 7;62(1):306-325. doi: 10.1088/1361-6560/62/1/306. Epub 2016 Dec 17.
We investigated the influence of model assumptions in GEANT4 Monte Carlo (MC) simulations for the calculation of monoenergetic and polyenergetic normalized glandular dose coefficients (DgN) in mammography, focussing on the effect of the skin thickness and composition, of the role of compression paddles and of the bremsstrahlung processes. We showed that selecting a skin thickness of 4 mm instead of 1.45 mm produced DgN values with deviations from 9% to 32% for x-ray spectra routinely adopted in mammography. Consideration of the bremsstrahlung radiation had a weak influence on monoenergetic DgN. Simulations (in the range 8-40 kVp) which included consideration of bremsstrahlung radiation, a skin thickness of 1.45 mm and a 2 mm thick compression paddles produced polyenergetic DgN coefficients up to 19% higher than corresponding literature data. Adding a 2 mm thick adipose layer between the skin layer and the radiosensitive portion of the breast produces polyenergetic DgN values up to 15% higher than those routinely adopted. These findings provide a quantitative estimate of the influence of model parameters on the calculation of the mean glandular dose in mammography.
我们研究了GEANT4蒙特卡罗(MC)模拟中的模型假设对乳腺摄影中计算单能和多能归一化腺体剂量系数(DgN)的影响,重点关注皮肤厚度和组成的影响、压迫板的作用以及轫致辐射过程。我们发现,对于乳腺摄影中常规采用的X射线光谱,选择4毫米的皮肤厚度而非1.45毫米会使DgN值产生9%至32%的偏差。考虑轫致辐射对单能DgN的影响较弱。在8 - 40 kVp范围内进行的模拟,包括考虑轫致辐射、1.45毫米的皮肤厚度和2毫米厚的压迫板,产生的多能DgN系数比相应的文献数据高出19%。在皮肤层和乳腺的放射敏感部分之间添加一层2毫米厚的脂肪层,会使多能DgN值比常规采用的值高出15%。这些发现提供了对模型参数对乳腺摄影中平均腺体剂量计算影响的定量估计。