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癌症免疫疗法:从实验室到临床应用——对癌症中心组织架构的潜在影响

Cancer immunotherapy: from the lab to clinical applications-Potential impact on cancer centres' organisation.

作者信息

Cairns Linda, Aspeslagh Sandrine, Anichini Andrea, Kyte Jon Amund, Blank Christian, Ascierto Paolo, Rekers Nicolle, Straten Per Thor, Awada Ahmad

机构信息

European Institute of Oncology, Via Ripamonti, 435, 20141 Milan. Italy.

Gustave Roussy, 114 rue Edouard Vaillant, 94805 Villejuif cedex, France.

出版信息

Ecancermedicalscience. 2016 Nov 10;10:691. doi: 10.3332/ecancer.2016.691. eCollection 2016.

Abstract

This report covers the Immunotherapy sessions of the 2016 Organisation of European Cancer Institutes (OECI) Oncology Days meeting, which was held on 15th-17th June 2016 in Brussels, Belgium. Immunotherapy is a potential cancer treatment that uses an individual's immune system to fight the tumour. In recent years significant advances have been made in this field in the treatment of several advanced cancers. Cancer immunotherapies include monoclonal antibodies that are designed to attack a very specific part of the cancer cell and immune checkpoint inhibitors which are molecules that stimulate or block the inhibition of the immune system. Other cancer immunotherapies include vaccines and T cell infusions. This report will summarise some of the research that is going on in this field and will give us an update on where we are at present.

摘要

本报告涵盖了2016年欧洲癌症研究所组织(OECI)肿瘤学日会议的免疫治疗环节,该会议于2016年6月15日至17日在比利时布鲁塞尔举行。免疫治疗是一种利用个体免疫系统对抗肿瘤的潜在癌症治疗方法。近年来,该领域在几种晚期癌症的治疗方面取得了重大进展。癌症免疫疗法包括旨在攻击癌细胞非常特定部位的单克隆抗体以及作为刺激或阻断免疫系统抑制作用的分子的免疫检查点抑制剂。其他癌症免疫疗法包括疫苗和T细胞输注。本报告将总结该领域正在进行的一些研究,并为我们提供当前进展情况的最新信息。

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