口腔生物流体生物标志物研究：现状与新前沿
Oral Biofluid Biomarker Research: Current Status and Emerging Frontiers.
作者信息
Wang Austin, Wang Chris P, Tu Michael, Wong David T W
机构信息
School of Dentistry, University of California at Los Angeles, Los Angeles, CA 90095, USA.
出版信息
Diagnostics (Basel). 2016 Dec 17;6(4):45. doi: 10.3390/diagnostics6040045.
Abstract
Salivary diagnostics is a rapidly advancing field that offers clinicians and patients the potential of rapid, noninvasive diagnostics with excellent accuracy. In order for the complete realization of the potential of saliva, however, extensive profiling of constituents must be conducted and diagnostic biomarkers must be thoroughly validated. This article briefly overviews the process of conducting a study of salivary biomarkers in a patient cohort and highlights the studies that have been conducted on different classes of molecules in the saliva. Emerging frontiers in salivary diagnostics research that may significantly advance the field will also be highlighted.
摘要
唾液诊断是一个快速发展的领域，它为临床医生和患者提供了进行快速、无创诊断且准确性极高的潜力。然而，为了充分实现唾液的潜力，必须对其成分进行广泛分析，并且必须彻底验证诊断生物标志物。本文简要概述了在患者队列中开展唾液生物标志物研究的过程，并重点介绍了针对唾液中不同类别分子所进行的研究。还将突出唾液诊断研究中可能显著推动该领域发展的新兴前沿领域。
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