Haelens Annemie, Roche Laurent, Bastos Joana, Woronoff Anne-Sophie, Zorzi Manuel, Francart Julie
aBelgian Cancer Registry, rue Royale, Brussels, Belgium bDepartment of Biostatistics, University Hospital of Lyon cCNRS, UMR 5558, Biometry and Evolutionary Biology Laboratory (LBBE), BioMaths-Health Department, Villeurbanne dUniversity of Lyon 1, Lyon, France eRegional Oncology Registry of the Centre, Portuguese Oncology Institute of Coimbra fDoubs and Belfort Territory Cancer Registry, EA3181, University Hospital of Besançon, Besançon gVeneto Tumour Registry, Veneto Region, Padua, Italy.
Eur J Cancer Prev. 2017 Jan;26 Trends in cancer net survival in six European Latin Countries: the SUDCAN study:S92-S99. doi: 10.1097/CEJ.0000000000000292.
Cancer survival is a key measure of the effectiveness of a healthcare system. As differences in healthcare systems are present among European Latin countries, it is of interest to look specifically at their similarities and differences in terms of cancer survival. Incident cases were extracted from the EUROCARE-V database for France, Italy, Spain, Switzerland, Portugal, and Belgium. One and 5-year net survivals (NS) were calculated for the period 2000-2004 using the Pohar-Perme estimator. Trends in NS over the 1992-2004 period and changes in the pattern of cancer excess mortality rate until 5 years after diagnosis were examined using a multivariate excess mortality rate model. There were moderate differences in age-standardized NS between countries (5-year NS range: 83-88%), but significant differences in the age groups 15-54 and 55-74 years (at 5 years up to +16 and +18% between any two countries). During the study period, excess mortality and NS improved in Italy, Spain, and Portugal. In Italy and Portugal, this improvement was slightly similar at ages 40, 55, and 70 whereas, in Spain, there was a sharp increase in NS at age 55. Because of this improvement, excess mortality and NS were similar in all six countries in 2004. Excess mortality peaked around 1 year after diagnosis in the youngest ages, but decreased gradually in the elderly. Detailed analyses showed differences in excess mortality and NS from cervical cancer between European Latin countries. However, these differences decreased over the study period because of the considerable improvement in Spain, Italy, and Portugal.
癌症生存率是衡量医疗保健系统有效性的关键指标。由于欧洲拉丁国家的医疗保健系统存在差异，因此特别关注它们在癌症生存率方面的异同很有意义。从EUROCARE-V数据库中提取了法国、意大利、西班牙、瑞士、葡萄牙和比利时的发病病例。使用Pohar-Perme估计器计算了2000 - 2004年期间的1年和5年净生存率（NS）。使用多变量超额死亡率模型研究了1992 - 2004年期间NS的趋势以及诊断后5年内癌症超额死亡率模式的变化。各国之间年龄标准化的NS存在适度差异（5年NS范围：83 - 88%），但在15 - 54岁和55 - 74岁年龄组存在显著差异（5年时，任意两个国家之间相差高达16%和18%）。在研究期间，意大利、西班牙和葡萄牙的超额死亡率和NS有所改善。在意大利和葡萄牙，40岁、55岁和70岁时的改善情况略有相似，而在西班牙，55岁时NS急剧上升。由于这种改善，2004年所有六个国家的超额死亡率和NS相似。最年轻年龄组的超额死亡率在诊断后约1年达到峰值，但在老年人中逐渐下降。详细分析显示欧洲拉丁国家宫颈癌的超额死亡率和NS存在差异。然而，由于西班牙、意大利和葡萄牙的显著改善，这些差异在研究期间有所减小。
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