Ezejimofor Martinsixtus C, Uthman Olalekan A, Maduka Omosivie, Ezeabasili Aloysius C, Onwuchekwa Arthur C, Ezejimofor Benedeth C, Asuquo Eme, Chen Yen-Fu, Stranges Saverio, Kandala Ngianga-Bakwin
Division of Health Sciences, University of Warwick Medical School, Coventry, CV4 7AL, UK.
Division of Health Sciences, University of Warwick Medical School, Coventry, CV4 7AL, UK; Warwick-Centre for Applied Health Research and Delivery (WCAHRD), Division of Health Sciences, University of Warwick Medical School, Coventry, UK; Liverpool School of Tropical Medicine, International Health Group, Liverpool, UK.
J Neurol Sci. 2017 Jan 15;372:262-269. doi: 10.1016/j.jns.2016.11.059. Epub 2016 Nov 25.
The burden of stroke has been projected to increase in low-and middle-income countries due to the ongoing epidemiological transition. However, community-based stroke prevalence studies are sparse in sub-Saharan Africa particularly in Nigeria. This study aimed to provide a comparative estimate of the prevalence of stroke survivors in the rural Niger Delta region. A three-phased door-to-door survey was conducted using WHO modified instruments. In the first-phase, 2028 adults (≥18years) participants randomly selected from two rural communities were screened by trained health research assistants for probable stroke. In the second phase, suspected cases were screened with stroke-specific tool. Positive cases were made to undergo complete neurological evaluation by two study neurologist in phase-three. Stroke diagnosis was based on clinical evaluation using WHO criteria. Overall, 27 (8 first-ever and 19 recurrent cases) stroke survivors with crude prevalence of 13.31/1000 (95% CI, 8.32-18.31) and a non-significant difference in prevalence between the two study communities were found, (P=0.393I). In addition, age-adjusted prevalence of stroke survivors was 14.6/1000 person, about 7-folds higher than previous estimates outside the Niger Delta region. The prevalence increases significantly with advancing in age, P<0·001. Among others, hypertension (92.59%) was the commonest risk factor and comorbidity found. Improved stroke surveillance and care, as well as better management of the underlying risk factors, primarily undetected or uncontrolled high blood pressure, remains a public health priority.
由于正在进行的流行病学转变,预计低收入和中等收入国家的中风负担将会增加。然而,撒哈拉以南非洲地区,尤其是尼日利亚,基于社区的中风患病率研究较少。本研究旨在对尼日尔三角洲农村地区中风幸存者的患病率进行比较估计。采用世界卫生组织修改后的工具进行了三个阶段的挨家挨户调查。在第一阶段,从两个农村社区随机抽取2028名成年人(≥18岁)参与者,由经过培训的健康研究助理进行可能中风的筛查。在第二阶段,使用中风特异性工具对疑似病例进行筛查。在第三阶段,由两名研究神经科医生对阳性病例进行全面的神经学评估。中风诊断基于使用世界卫生组织标准的临床评估。总体而言,共发现27名(8例初发和19例复发)中风幸存者,粗患病率为13.31/1000(95%可信区间,8.32 - 18.31),两个研究社区之间的患病率无显著差异(P = 0.393)。此外,中风幸存者的年龄调整患病率为14.6/1000人,比尼日尔三角洲地区以外的先前估计高出约7倍。患病率随年龄增长显著增加,P < 0.001。其中,高血压(92.59%)是最常见的危险因素和合并症。改善中风监测和护理,以及更好地管理主要未被发现或未得到控制的潜在危险因素——高血压,仍然是公共卫生的优先事项。