大豆苷元、染料木黄酮和鹰嘴豆芽素A的微生物糖基化：鹰嘴豆芽素A的两种新葡糖苷。
Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A.
作者信息
Sordon Sandra, Popłoński Jarosław, Tronina Tomasz, Huszcza Ewa
机构信息
Department of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland.
出版信息
Molecules. 2017 Jan 3;22(1):81. doi: 10.3390/molecules22010081.
Biotransformation of daidzein, genistein and biochanin A by three selected filamentous fungi was investigated. As a result of biotransformations, six glycosylation products were obtained. Fungus converted all tested isoflavones to 4″--methyl-7--glucosyl derivatives, whereas and were able to transform genistein and biochanin A to genistin and sissotrin, respectively. In the culture of , in addition to the sissotrin, the product of glucosylation at position 5 was formed. Two of the obtained compounds have not been published so far: 4″--methyl-7--glucosyl biochanin A and 5-glucosyl biochanin A (isosissotrin). Biotransformation products were obtained with 22%-40% isolated yield.
研究了三种选定丝状真菌对大豆苷元、染料木黄酮和鹰嘴豆芽素A的生物转化。生物转化的结果是得到了六种糖基化产物。真菌将所有测试的异黄酮转化为4″-甲基-7-葡萄糖基衍生物，而[此处可能有信息缺失]和[此处可能有信息缺失]能够分别将染料木黄酮和鹰嘴豆芽素A转化为染料木苷和芒柄花苷。在[此处可能有信息缺失]的培养物中，除了芒柄花苷外，还形成了5位糖基化产物。所得到的两种化合物迄今尚未见报道：4″-甲基-7-葡萄糖基鹰嘴豆芽素A和5-葡萄糖基鹰嘴豆芽素A（异芒柄花苷）。生物转化产物的分离产率为22%-40%。
Zotero 插件